🔬 FRAmework-01 | Now Enrolling A phase 3 trial evaluating a FRα-targeting ADC in patients with Ovarian Cancer. Key details: - Enrolling PSOC and PROC - All FRα expression levels - Allows prior mirvetuximab Click the image for trial & enrollment info

My new arXiv paper just dropped and it shows thermodynamics is downstream of logic. If you replace the concept of physical energy with a simple cost of distinguishability, J(x) = cosh(log x) - 1, the Boltzmann-Gibbs distribution emerges exactly. The same law that gives us α ≈ 1/137 and 3D space also gives us statistical mechanics.

BioVie $BIVI: SUNRISE-PD Phase 2b Trial Completes Last Patient Visit — Topline Parkinson's Data on Track for Q3 2026 $BIVI has completed the final patient evaluation visit in its SUNRISE-PD Phase 2b trial, a 57-patient, randomized, double-blind, placebo-controlled study evaluating bezisterim in early-stage Parkinson's disease patients who have not yet been treated with carbidopa/levodopa. The company is now entering the study closeout process, with topline results expected in Q3 2026. SUNRISE-PD was specifically designed to quantify the magnitude of bezisterim's therapeutic impact on motor function, sleep disorder, anxiety, depression, and cognitive slowness, with the explicit goal of finalizing the design for Phase 3 registrational trials. This readout is the blueprint decision point for the path to potential approval. In prior clinical work, bezisterim has shown signals of improved motor control, reduced neuroinflammation, and improved "morning on" symptoms in Parkinson's patients. Why Investors Should Be Watching: • Topline data catalyst in Q3 2026 • Results are designed to inform Phase 3 registrational trial design — this is a structural milestone, not just a data point • Bezisterim targets TNFα-mediated inflammation and insulin resistance, a differentiated mechanism in a disease space with significant unmet need • A recent KOL event featuring a Brown University neuropathologist reinforced the scientific rationale behind bezisterim's approach to neurodegeneration • Long COVID Phase 2 topline data also expected Summer 2026, providing a second near-term catalyst For investors tracking $BIVI, Q3 2026 is shaping up as a defining period — one readout that could set the Phase 3 course for bezisterim in Parkinson's, and a second from the Long COVID program arriving around the same time. Read the full announcement: $BIVI $SXTP $INAB $DMAC $BFRG $NSRX $CLDI $NXL $CNTB $LTRN $KYNB $ANIX