Tentative bottom line: ATP synthase dimer angles could become a powerful structural biomarker of mitochondrial health. If cardiolipin composition influences ATP synthase geometry, and that geometry influences cristae architecture, measuring dimer angles could provide a readout of mitochondrial structural integrity that conventional protein-abundance measurements miss. The 2025 study makes this particularly interesting: simulated healthy cardiolipin membranes produced ATP synthase dimer angles of approximately 73° versus 65° in Barth syndrome-like membranes.

First at @FOS: Officials at several combined ATP and WTA tournaments say they've received interest from prediction-market companies. Earlier this week, the US Open announced a partnership with Kalshi, first reported by @BenHorney. More ⬇️

Denmark’s state-backed pension fund ATP, which has been under fire over recent investment missteps, should reassess its heavy exposure to domestic stocks, according to an independent strategy review