Colossal Biosciences, the de-extinction startup trying to revive species like the dire wolf and woolly mammoth, is reportedly in talks to raise new funding at a $20 billion to $30 billion valuation. Roughly 2x to 3x jump in valuation from early 2025.

The biosecurity landscape is rapidly evolving. To stay ahead of future outbreaks, we’re partnering with @IsomorphicLabs to outline our approach to bioresilience. Here’s how we’re deploying frontier AI to build proactive defenses for global health →

Geopolitical conservatism in biotech risks becoming anti-progress. Biosecurity matters but scientific talent is globally distributed and the tools for discovery should be too. @metanova_labs mission is more important than ever. Decentralized, permissionless infrastructure isn't just an ideological position — it's a practical response to a growing problem that ultimately affects all of us. Immigration to the global centers where institutions, capital, and infrastructure are concentrated is harder than ever. At the same time, access to frontier AI is increasingly determined by jurisdiction. As evidenced by @AnthropicAI recent restrictions on Fable and others, the tools that enable scientific discovery are becoming concentrated within a relatively small number of (or single) countries. This has implications for who can contribute to scientific innovation and from where. Roughly 2/3 of Nobel science laureates were not born in the United States, and approximately 40% of U.S. Nobel science prizes awarded since 2000 went to immigrants. Meanwhile, proposals such as a $100k H-1B fee, travel restrictions affecting dozens of countries, and compute export controls under the BIS AI Diffusion Framework are making participation in frontier research increasingly unequal. If similar restrictions had existed throughout the last century, many of the discoveries, companies, and medicines we rely on today may never have emerged. #Bittensor# offers a market-driven alternative for coordinating talent, capital, compute, and scientific innovation across borders.

Ken Levine, the creator of BioShock, recently shared his views on new gaming hardware and pointed out that the upcoming Nintendo Switch 2 and Valve’s new Steam Machine are not big technological jumps. “Look at, say, the Switch 2 and even the new Steam Machine coming out. Those are not massive technological upgrades. That wasn’t their strategy. I think people are realising we’re hitting a bit of diminishing returns with that,” Levine explained that his team avoids ultra-realistic graphics because it is expensive and does not age well, preferring stylized art that lasts longer like in BioShock. He believes real innovation comes from strong stories, artistic choices, and meaningful player decisions rather than raw power, and his new game Judas uses this approach, similar to the success of Baldur’s Gate 3. “If you have the right art director and the right approach, you don’t need to be on the cutting edge of technology all the time.”

🇯🇵 Remind number #694837# to ignore every single so-called "Japanese" influencer who has pronouns or Muslim flags in their bios. They're brainwashed people who went to school in a western country.