Peripheral artery disease affects 200M+ people worldwide, and restoring blood flow isn’t enough to repair damaged muscle. @WesternU researcher @HaoYin20 raised $10k on ResearchHub to investigate why. Now published as a Stage 1 Registered Report in @RHubJournal, Hao's project will test whether Sirt6 loss in vessel-support cells triggers a “senescence secretome” that actively blocks muscle recovery after ischemia. If confirmed, it could point to new therapeutic targets for one of the world's most common vascular diseases. Track the project here:

Recent developments suggest that tokenized securities are entering a new phase of adoption. As markets evolve toward models such as continuous trading , governance, settlement, and interoperability become critical to long-term resilience. These are core market infrastructure considerations, not peripheral issues. DTCC’s role is to help ensure tokenized markets are supported by established post trade foundations designed for scale, risk management, and trust. Learn more: