Keep in mind re: the path of Isaias that the east side of the storm will generate storm surge while areas on the western side of the storm could see water sucked out.
If the storm makes landfall in Pensacola as the NHC suggests, it would likely cause water to recede in Mobile Bay while producing storm surge throughout the FL panhandle.
If it enters along the lines of the models that have it coming ashore in Mobile, that will still yield major storm surge for NW FL counties.