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Hardik Shah
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๊ฐ€์ž… September 2009
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๐Ÿ“ข ๐—๐—จ๐—ฆ๐—ง ๐—œ๐—ก: $LLY Eli Lilly to Acquire Merida Biosciences for Up to $2.875 Billion ๐Ÿ‘‰ ๐—ž๐—ฒ๐˜† ๐—›๐—ถ๐—ด๐—ต๐—น๐—ถ๐—ด๐—ต๐˜๐˜€: โžค ๐—˜๐—น๐—ถ ๐—Ÿ๐—ถ๐—น๐—น๐˜† will acquire ๐— ๐—ฒ๐—ฟ๐—ถ๐—ฑ๐—ฎ ๐—•๐—ถ๐—ผ๐˜€๐—ฐ๐—ถ๐—ฒ๐—ป๐—ฐ๐—ฒ๐˜€ for up to $๐Ÿฎ.๐Ÿด๐Ÿณ๐Ÿฑ ๐—ฏ๐—ถ๐—น๐—น๐—ถ๐—ผ๐—ป. โžค Deal includes an upfront cash payment plus contingent milestone payments. โžค Acquisition strengthens Lilly's pipeline across ๐—ฎ๐˜‚๐˜๐—ผ๐—ถ๐—บ๐—บ๐˜‚๐—ป๐—ฒ and ๐—ฎ๐—น๐—น๐—ฒ๐—ฟ๐—ด๐—ถ๐—ฐ diseases. โžค Merida's platform selectively degrades ๐—ฑ๐—ถ๐˜€๐—ฒ๐—ฎ๐˜€๐—ฒ-๐—ฐ๐—ฎ๐˜‚๐˜€๐—ถ๐—ป๐—ด ๐—ฎ๐˜‚๐˜๐—ผ๐—ฎ๐—ป๐˜๐—ถ๐—ฏ๐—ผ๐—ฑ๐—ถ๐—ฒ๐˜€ while preserving normal immune function. โžค Lead candidate ๐— ๐—˜๐—ฅ๐Ÿฑ๐Ÿญ๐Ÿญ is in Phase 1 development. โžค MER511 targets ๐—š๐—ฟ๐—ฎ๐˜ƒ๐—ฒ๐˜€' ๐—ฑ๐—ถ๐˜€๐—ฒ๐—ฎ๐˜€๐—ฒ and thyroid eye disease. โžค Initial Phase 1 data showed robust ๐—ฝ๐—ฎ๐˜๐—ต๐—ผ๐—ด๐—ฒ๐—ป๐—ถ๐—ฐ ๐—ฎ๐—ป๐˜๐—ถ๐—ฏ๐—ผ๐—ฑ๐˜† reductions. โžค Merida's pipeline also includes ๐— ๐—˜๐—ฅ๐Ÿณ๐Ÿฒ๐Ÿต targeting multiple allergic diseases. โžค Transaction is expected to close in the ๐—ณ๐—ผ๐˜‚๐—ฟ๐˜๐—ต ๐—พ๐˜‚๐—ฎ๐—ฟ๐˜๐—ฒ๐—ฟ ๐—ผ๐—ณ ๐Ÿฎ๐Ÿฌ๐Ÿฎ๐Ÿฒ. ๐Ÿ‘‰ ๐—ช๐—ต๐˜† ๐—ง๐—ต๐—ถ๐˜€ ๐— ๐—ฎ๐˜๐˜๐—ฒ๐—ฟ๐˜€: โžค Adds a differentiated ๐—ฝ๐—ฟ๐—ฒ๐—ฐ๐—ถ๐˜€๐—ถ๐—ผ๐—ป ๐—ถ๐—บ๐—บ๐˜‚๐—ป๐—ผ๐—น๐—ผ๐—ด๐˜† platform to Lilly's pipeline. โžค Approach targets disease-causing antibodies rather than broadly suppressing immune function. โžค Platform could potentially address numerous ๐—ฎ๐—ป๐˜๐—ถ๐—ฏ๐—ผ๐—ฑ๐˜†-๐—ฑ๐—ฟ๐—ถ๐˜ƒ๐—ฒ๐—ป diseases beyond its lead indication. โžค Deal expands Lilly's exposure to high-unmet-need ๐—ฎ๐˜‚๐˜๐—ผ๐—ถ๐—บ๐—บ๐˜‚๐—ป๐—ฒ therapeutics. ๐Ÿ‘‰ ๐—˜๐˜…๐—ฝ๐—ฒ๐—ฟ๐˜ ๐—ฆ๐˜๐—ฎ๐˜๐—ฒ๐—บ๐—ฒ๐—ป๐˜๐˜€: ๐—™๐—ฟ๐—ฎ๐—ป๐—ฐ๐—ถ๐˜€๐—ฐ๐—ผ ๐—ฅ๐—ฎ๐—บรญ๐—ฟ๐—ฒ๐˜‡-๐—ฉ๐—ฎ๐—น๐—น๐—ฒ, ๐— .๐——., ๐—ฃ๐—ต.๐——., Senior Vice President, Lilly Immunology Research and Early Clinical Development: "We're building our pipeline around therapies that meaningfully change the course of disease, not just its downstream effects. Merida's lead program is designed to do exactly that: selectively and directly eliminating the autoantibodies causing Graves' disease and thyroid eye disease, while preserving normal immune function, with initial Phase 1 data already pointing to the potential for improved efficacy and safety," said Francisco Ramรญrez-Valle, M.D., Ph.D., senior vice president, Lilly immunology research and early clinical development. "We see potential to apply this precision approach across a broad range of antibody-driven diseases, and we look forward to advancing this novel technology working with the Merida team." ๐—”๐—ฑ๐—ฎ๐—บ ๐—ง๐—ผ๐˜„๐—ป๐˜€๐—ฒ๐—ป๐—ฑ, Chief Executive Officer of Merida: "Merida was founded to fundamentally change how autoimmune and allergic diseases are treated, by targeting the antibodies driving them directly, rather than suppressing the immune system broadly. Under our CSO and founder Dario Gutierrez's scientific leadership, our team has advanced that idea from concept to clinical data, and what we've seen so far reinforces our conviction that this approach can make a meaningful difference for patients," said Adam Townsend, chief executive officer of Merida. "Today's announcement reflects the hard work of the entire Merida team, and joining Lilly gives our science the resources and commitment to realize its potential for patients with immune-mediated conditions."
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