Manchurius Hao — Greeks.live 首席赌狗
@AntonLaVay
Nec temere, nec timide. 🇳🇱🇪🇺🇨🇳 能源/科技/BIO
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가입 August 2015
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Claude 可以在 21 小时里筛：
20 万个 reverse transcriptases，
找到 3,500 个 candidate systems，
最后筛出几十个值得真正研究的东西。
但 AI 找到 sequence 以后，不能靠 token 验证。
你得：
合成 DNA、构建 gene、表达 protein、修改 sequence、重新合成、再实验。
这正好是 $TWST 的位置。
而 $TWST 自己今年已经明确表示，AI-guided protein design 正在增加复杂 synthetic genes 的需求。
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Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR.
We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use.
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