We have found crypto to be incredibly effective at incentivizing quantity AND quality with the right incentive design. For example in only 2 weeks running our nanobody design competition we saw: • Binding confidence: up ~3x from first to last submission • Structural fit: uncertainty at the interface dropped by nearly half • Hydrogen bonds: grow steadily across all designs. As well as in our chemical search algorithm competition, where a miner introduced an optimization strategy never applied to drug discovery before (not just quality but novelty). This strategy has continued to be improved across challenges and consistently outperforms a published benchmark across different targets. You can see our progress live on our dashboard: