Zach Wu(@ZvxyWu):In collaboration with the @francesarnold and @pengliu_group research groups, we @GoogleDeepMind are proud to release AlphaProtein Novo, a pipeline for small-molecule enzyme design. We developed AlphaProtein Novo on a few standard model reactions, and validated designs in our own wet lab. We then wanted to challenge this system against nascent chemistries, so we asked leading scientists in biocatalysis whether we could partner on the reactions they cared about.

Zach Wu

@ZvxyWu

RS at Google Deepmind, previously Arnold research group at Caltech. Views my own.

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Zach Wu@ZvxyWu

2026.10.05 15:19

In collaboration with the @francesarnold and @pengliu_group research groups, we @GoogleDeepMind are proud to release AlphaProtein Novo, a pipeline for small-molecule enzyme design. We developed AlphaProtein Novo on a few standard model reactions, and validated designs in our own wet lab. We then wanted to challenge this system against nascent chemistries, so we asked leading scientists in biocatalysis whether we could partner on the reactions they cared about.