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AI drug discovery may be finding its real scaling law. 🧬 As Claude and other frontier models move deeper into biology, the bottleneck is shifting from model capability to proprietary biological data and real-world feedback. That puts companies with unique data assets in focus. $TEM, for example, has built 500+ PB of molecular and clinical data across 45M+ de-identified patient journeys. The next AI drug race may be less about who has the biggest model — and more about who can build the fastest data → prediction → validation → feedback loop. Trade $TEM on StableStock: → #AIDrugDiscovery# #Biotech# #TEM# Not investment advice. For informational purposes only.
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🧬 Just saying "generate peptides with anticancer activity and low toxicity" in plain language is now enough to steer a molecule generator toward that goal. Title: LLM-to-Flow Distillation: Teaching Natural Language Goals to Scientific Generators URL: Flow and diffusion models are great at generating valid molecules and peptides, but aligning them to a natural-language goal usually needed an explicit proxy reward. This paper's LFD removes that requirement by turning an LLM into a teacher for a pretrained generator student. Here are 3 highlights. 🎯 No proxy reward needed to hit the goal The LLM watches the generator's current samples and sets an achievable sub-goal step by step, nudging the generator toward the target region via DPO, round after round. 📊 Absolute scores are unreliable, but relative judgments aren't Asking the LLM for a 1-100 score gives numbers far off from ground truth, but which-is-better pairwise judgments stay consistently reliable, which is why LFD uses a scalable batch-classification scheme instead of pairwise duels. 🏆 Consistently beats existing methods LFD hits 69.06% pLM4CPPs for cell-penetrating peptides (vs. 57.04% for DiffusionNFT), 53.54% for anticancer peptides (vs. 35.94% for Guidance), and the best Vina score of -8.48 for dopamine D2 receptor docking among all methods. This feels especially valuable for real experimental science, where a clean proxy reward usually isn't available. #LLM# #AIDrugDiscovery#
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