Treating #CLTI# starts with addressing one of its biggest challenges: vascular calcification. Because calcium limits vessel compliance and can complicate endovascular treatment, effective calcium modification has become critical to achieving durable outcomes. With its mechanism of action, #ShockwaveIVL# selectively fractures calcium while minimizing vessel injury, helping optimize treatment across the peripheral vasculature, including below-the-knee interventions with #ShockwaveE8# on patients with CLTI. 💡Read more in the Vascular News September supplement. #CLTI# #PAD# #ShockwaveIVL# #PeripheralIVL# #VascularHealth# #MoA# #JNJMedTechProud# US Rx only. Safety Info:  Product availability may vary by country.

In many ways, I am 18. If an alien encountered me, they’d struggle to distinguish me from my son. I know this seems impossible. I also know I look my age, 49. But here are the ways I am indistinguishable from an 18 year old: > Sleep quality > Erection function > Fertility > Resting heart rate > Vascular health > Cardiovascular health > Blood pressure > Metabolic health > Blood glucose control > Bone mineral density > Muscle > Fat > Inflammation (undetectable) > Shitposting And here are some ways I am my age: > Hearing > Somatic mutations Friends, I think I’ve done something no one else has ever done: I am more 18 than I am 49. This is the first rep and we are still figuring things out, but it points toward our inevitable future: better technology and therapies will make youthful vibrance the default. If you’re in your 30s, 40s, 50s, 60s, and wondering if you can do the same, the answer is yes. If you’re a teen or in your 20s and feel awful, you can too. These results only took me 5 years to achieve. The most powerful things are free, and gated only by choice. It feels amazing. I feel nimble, and spry, and excited by the world. I hope you join me in saying yes to life and no to die culture.

Massive blood draw today: > 47 tubes > 250 mL What I'm measuring: > single cell sequencing of circulating immune cells > inflammation, oxidative stress, vascular health > metabolic, lipid, blood glucose regulation > brain