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Love this post by @antirez on developing Redis Array support. Its a great showcase of thoughtful AI usage and how AI can empower even the best developers while still producing high quality work.
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🚨 OPEN SOURCE AI IS LITERALLY UNSTOPPABLE 🚨 The legendary founder of Redis (Antirez) just dropped ds4 - a custom native inference engine built specifically for DeepSeek v4 Flash This is earth shattering! Here is why: DeepSeek v4 Flash is a quasi-frontier model with a massive 1M context window You can now run it LOCALLY on a 128GB Mac using specialized 2-bit quantization The architecture is reimagined—he moved the KV cache from RAM directly to the SSD disk! 🤯 We already know DeepSeek v4 Flash is insanely good for agentic loops - Now you don't even need the cloud to run it Closed-source labs are burning tens of billions on massive GPU clusters while single brilliant developers are running frontier-level AI on laptops! They told us open-source would be worthless against trillion-dollar monopolies Instead, pure hacker culture + incredible open-weight models are completely rewriting the rules Open Source will ALWAYS win 💕
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Small experiment: I'm using my Pi coding sessions as calibration data for a new DeepSeek V4 Flash Q2 quant, via antirez's ds4 imatrix machinery. Absolutely no expectations, but I'm curious to see what happens. Not sure how to eval though.
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Thank you to the staff at the facility and to @AntiRecidivism, @ScottyBudnick and @samwlewis1 for having me. Happy Thanksgiving to all of the men and women that are away from their families this year.
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HIV just got dethroned. What was once a death sentence is now something millions live with — quietly, normally, for decades. Modern antiretroviral therapy has flipped the script. People diagnosed today, who take their meds consistently, can expect a near-normal lifespan. The virus stays buried. Undetectable. Untransmittable. Let that sink in. A diagnosis that wiped out a generation in the 80s and 90s is now a manageable condition — closer to diabetes than to doom. And the science isn't stopping there. Gilead's once-daily single-tablet BIC/LEN regimen is under FDA priority review with a decision expected August 27, 2026. One pill. Once a day. That's it. At CROI 2026 in Denver, the RIO cure trial showed over half of participants kept their viral load undetectable for more than 20 weeks after stopping treatment entirely. Two have been off meds for over a year. A 62-year-old Canadian man — now known as the Toronto patient — was announced likely cured in April 2026 after a stem cell transplant. Yale researchers cracked open a hidden mechanism called circHIV that could become the next major drug target. Case Western turned the immune system's own Natural Killer cells into HIV-hunting weapons. Oxford is using broadly neutralising antibodies to keep the virus in check long after pills are gone. The hunt for a full, scalable cure is no longer science fiction. It's a research pipeline with real names, real patients, and real timelines. HIV used to mean counting the years you had left. Now it means living them. Source: Aidsmap (CROI 2026), Gilead Sciences, amfAR, Weill Cornell Medicine, Yale News, Case Western Reserve University
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