Geopolitical alignment can significantly impact global economic growth, and rising fragmentation in the past decade has cut close to 1% cumulatively from global GDP. Read more from Goldman Sachs Research:

Geopolitical conservatism in biotech risks becoming anti-progress. Biosecurity matters but scientific talent is globally distributed and the tools for discovery should be too. @metanova_labs mission is more important than ever. Decentralized, permissionless infrastructure isn't just an ideological position — it's a practical response to a growing problem that ultimately affects all of us. Immigration to the global centers where institutions, capital, and infrastructure are concentrated is harder than ever. At the same time, access to frontier AI is increasingly determined by jurisdiction. As evidenced by @AnthropicAI recent restrictions on Fable and others, the tools that enable scientific discovery are becoming concentrated within a relatively small number of (or single) countries. This has implications for who can contribute to scientific innovation and from where. Roughly 2/3 of Nobel science laureates were not born in the United States, and approximately 40% of U.S. Nobel science prizes awarded since 2000 went to immigrants. Meanwhile, proposals such as a $100k H-1B fee, travel restrictions affecting dozens of countries, and compute export controls under the BIS AI Diffusion Framework are making participation in frontier research increasingly unequal. If similar restrictions had existed throughout the last century, many of the discoveries, companies, and medicines we rely on today may never have emerged. #Bittensor# offers a market-driven alternative for coordinating talent, capital, compute, and scientific innovation across borders.

Geopolitical risk is no longer a backdrop. It’s a core driver of markets. The latest article from the Morgan Stanley Institute explores how global tensions are shaping investment outcomes and why staying ahead of these shifts matters more than ever.

🟢 Geopolitical de-escalation sparks $618M in net taker volume, wiping out Bitcoin shorts This weekend, which looked set to be complicated on the geopolitical front, ended with the abandonment of a massive military operation that the United States had been preparing. This positive news, relayed last night, allowed markets to wake up in the green. That was all speculators needed to shake up the Bitcoin derivatives market hard this morning. Within an hour, net taker volume jumped from +$11 million to +$618 million on Binance at the opening of European markets. It is fairly rare to see this much buying power flow into derivatives in such a short time. This burst of positivity liquidated more than $400 million in short positions across the entire crypto market, helping Bitcoin break above $85 000. This marks a trend change, as it is a break of structure relative to the May high. Despite a context that remains tense, Bitcoin appears to be continuing its momentum, notably fueled by investors who still don't believe in it and are positioning against the crowd.

Any geopolitical headlines or handwringing around Russia/NATO is a spectacular opportunity to buy dips. I don’t talk about this (this account is focused on crypto) but I’ve been very plugged into the osint community around the Ukraine conflict since before it even broke out. In the four years it’s been active, Russia hasn’t come close to achieving its operational goals, and the material losses it’s endured are so staggering that it almost defies description. The attrition and lockup of its dwindling resources is in full view, with critical infrastructure getting successfully hit over a thousand km behind front lines. Oil refineries and wildberries is the tip of the iceberg. And sort of implication that Russia is willing to open a second front of hot conflict on a NATO country is genuinely laughable. Crypto dips on this sort of thing are an instant buy

Evolving geopolitical dynamics are reshaping the global economy. Learn what investors should be watching as these trends continue to unfold in the latest newsletter from the Morgan Stanley Institute:

🚨⚡️ GEOPOLITICAL EARTHQUAKE IN BEIJING: Hours Remain Until the Moscow-Beijing Axis Launches a "New Era" that Defies the West! 🇷🇺🇨🇳 President Vladimir Putin will arrive in Beijing this evening, May 19, welcomed by Chinese Foreign Minister Wang Yi. This is no ordinary summit; Putin and Xi Jinping will officially adopt a landmark "Declaration on the Establishment of a Multipolar World and a New Type of International Relations," delivering a direct challenge to unipolar dominance. - High-Stakes Agenda & 40 Strategic Pacts: Closed-door and expanded-format negotiations will take place to redraw the global economic and political roadmap. The two leaders will hold detailed discussions on the massive "Power of Siberia - 2" gas pipeline project to solidify energy security. Signing roughly 40 joint documents designed to lock in deep structural ties across industry, transport, and nuclear energy. On May 20, the leaders will hold an intimate, informal "tea-time" session to break down the most critical and pressing international issues. - A Colossal Russian Influx in Beijing: Putin has effectively transferred the weight of the Russian state to China. He is backed by a massive delegation of top-tier officials and business titans, including Peskov, Lavrov, Manturov, and Novak, alongside billionaire oligarchs and energy czars like Sechin, Miller, Timchenko, and Deripaska. - Moving away from standard newspaper columns, Putin recorded a rare, direct video address to the citizens of the People's Republic of China. - The Kremlin explicitly confirmed there is absolutely no connection between Putin's historic summit and Donald Trump's upcoming schedule. This alliance moves entirely on its own sovereign merit.