LDL cholesterol is one of the most actionable things from a blood draw. A meta analysis of 49 randomized trials and 312,175 people found that every 39 mg/dL (1 mmol/L) reduction in LDL was associated with about 23% fewer major vascular events: heart attacks, strokes, cardiovascular death. Nutrition can some of the heavy lifting, dropping LDL levels by 13-14% over six months by combining viscous fiber, nuts, plant protein, and plant sterols. Medications can also serve a role.