How do inflammasomes drive CAPS?
A mass cytometry analysis decrypts how #NLRP3# mutations in patient neutrophils trigger the clustering of gasdermin D and E at the plasma membrane, leading to #pyroptosis# and the release of IL-1-beta. @UCSanDiego
How do inflammasomes drive CAPS?
A mass cytometry analysis decrypts how #NLRP3# mutations in patient neutrophils trigger the clustering of gasdermin D and E at the plasma membrane, leading to #pyroptosis# and the release of IL-1-beta. @UCSanDiego