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How do inflammasomes drive CAPS? A mass cytometry analysis decrypts how #NLRP3# mutations in patient neutrophils trigger the clustering of gasdermin D and E at the plasma membrane, leading to #pyroptosis# and the release of IL-1-beta. @UCSanDiego
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How do inflammasomes drive CAPS? A mass cytometry analysis decrypts how #NLRP3# mutations in patient neutrophils trigger the clustering of gasdermin D and E at the plasma membrane, leading to #pyroptosis# and the release of IL-1-beta. @UCSanDiego
Show more