GREG ISENBERG(@gregisenberg):The only businesses left to build: 1. AI native service firms 2. Offline businesses 3. Distribution (media, community, audience) 4. Proprietary datasets 5. Domain specific harnesses (the agent that runs one industry's work) 6. Robotics and physical AI 7. Physical products with a fan following 8. Compute and energy 9. Health, longevity, and care 10. Marketplaces and social networks (for people and agents) 11. Real assets (property, equipment, land, infrastructure) 12. Vertical agents 13. Security

GREG ISENBERG

@gregisenberg

I drop startup ideas daily. Host @startupideaspod. CEO: @latecheckoutplz we build companies like @ideabrowser, @meetLCA, @boringmarketer etc

Joined May 2008

997 Following 719.8K Followers

GREG ISENBERG@gregisenberg

2026.09.12 12:48

The only businesses left to build: 1. AI native service firms 2. Offline businesses 3. Distribution (media, community, audience) 4. Proprietary datasets 5. Domain specific harnesses (the agent that runs one industry's work) 6. Robotics and physical AI 7. Physical products with a fan following 8. Compute and energy 9. Health, longevity, and care 10. Marketplaces and social networks (for people and agents) 11. Real assets (property, equipment, land, infrastructure) 12. Vertical agents 13. Security