This may be one of the more important Healthcare specialized Local AI weight releases.
Ant open-sourced the weights for Ling-3.0-flash-Sante.
The model itself isn't new as Sante has been available through APIs since September but ...
What's new is 👉 you can now bring the healthcare model home.
Stats
🧠 124B total parameters
⚡ only ~5.1B active/token
📚 256K context
🩺 healthcare-specialized
🔎 deep research
🤖 multi-agent collaboration
🔧 tool use
It's built on the same Ling-3.0-flash architecture that already runs in llama.cpp.
For reference, base Ling-3.0-flash GGUFs already exist around
Q4_K_M → ~77GB
IQ3 → ~54GB
IQ2 → ~40–46GB
IQ1 → ~28–31GB
⚠️ Those are BASE Ling-3.0-flash quants. I haven't found an official Sante GGUF yet.
But now that the Sante weights are downloadable, this becomes a home model for
🖥️ 96/128GB workstations
🍎 high-memory Apple Silicon
⚡ DGX/RTX Spark-class unified memory
🔗 multi-GPU local systems
And healthcare is one of the places where Local AI can be useful for private documents + research + agent workflows can stay on hardware you control instead of being sent to a cloud API.
Ant also reports substantial healthcare gains in the new release, including
HealthBench Professional
45.73 → 54.29
AFUMED ComplexReasoning
65.22 → 76.92
Link in ALT