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MALAYSIAN PHARMACY CHAIN BIG CARING LAUNCHES ITS IPO AT A VALUATION OF UP TO $2B It is offering up to 1.9 billion shares at a maximum 1.08 ringgit each ahead of a November 19 debut, with 19 cornerstone investors including IFC and JPMorgan Asset Management, per Reuters.

$M Earnings: - Macy’s, Inc. net sales of $4.9 billion increased 1.1% versus last year. - Macy’s, Inc. comparable sales1 rose 2.7%, with go-forward comparable sales up 2.8%. - Macy’s comparable sales rose 1.1%, with a 1.9% increase for Reimagine 200 stores. - GAAP diluted EPS was $0.62, up 100%; Adjusted diluted EPS was $0.63, up 14% versus last year excluding a $0.23 net tariff refund benefit. - Bluemercury comparable sales increased 6.2%. - Bloomingdale’s comparable sales increased 11.3% and achieved its highest second-quarter sales volume in the brand’s history. “Our second-quarter performance builds on the progress our colleagues have consistently delivered through our Bold New Chapter strategy,” said Tony Spring, chairman and chief executive officer of Macy’s, Inc. “The investments we're making are driving results across our portfolio, from the continued outperformance of our Reimagine 200 Macy’s stores, to meaningful double-digit growth at Bloomingdale’s and another solid quarter at Bluemercury. As we enter the second half of the year, we remain focused on scaling what is resonating most with customers – exciting brands and assortments and compelling events and experiences. Combined with disciplined execution, we expect these efforts to continue to build a durable foundation for sustainable, profitable growth.”

Anthropic says Claude found a previously undescribed enzyme system in bacteriophage DNA. One research brief, a database of 1.9 billion protein clusters, roughly 950 agent sessions running 21 hours & consuming about 210 million tokens. The system is called ART: array-associated reverse transcriptase & has three parts: the enzyme, a partner gene of unknown function, & an array of 3 to 21 evenly spaced DNA repeats. The repeat layout is what drew the CRISPR comparison. In CRISPR, an array like that stores RNA guides, which is what makes the system programmable. Now the caveats, which matter more than the headline. The enzyme itself wasn't actually new, earlier studies had identified it. What's new is the recognition of the array & the partner protein alongside it. Nobody knows what ART does. Lab work confirmed the array is expressed as several short RNAs & that's where the biology currently stops. No demonstrated function, no gene-editing capability, preprint not peer-reviewed. Feng Zhang, one of CRISPR's pioneers, reviewed it & called the finding intriguing & worth further investigation, which is a careful scientist's phrasing, not an endorsement. Other researchers have been less impressed. 🤷‍♂️

US TRADE DEFICIT HITS LARGEST LEVEL SINCE MARCH 2025 The US goods trade deficit widened 2.1% to $134.9 billion in September, exceeding economists' expectations of $130.2 billion. Imports rose 2.4%, driven by a 7.5% surge in capital goods, including computers, semiconductors, and telecommunications equipment supporting AI data center expansion. Exports increased 2.6%, but failed to offset the growing import bill.

This week we logged the options-implied move before five earnings reports. All five stocks have moved less than that so far. Next up after today's close: $MSFT and $GOOGL , with implied moves of 5.1% and 5.9%, about $200 billion and $234 billion of market value. Their own history is mixed. Microsoft's last four report moves averaged 8.1%, including a 15.5% gain in July. Alphabet's averaged 5.0%, and it fell 7.1% in July. Norwegian Cruise Line $NCLH has the opposite record. Options imply about 7.9% for its report Thursday before the open. The stock fell more than that after each of its last four reports: 15.3%, 10.5%, 8.6% and 9.8%. Street estimates: Microsoft fiscal first-quarter adjusted EPS of $4.72 on $90.7 billion of revenue, vs. $4.13 and $77.7 billion a year ago. Alphabet, $3.01 on $127.9 billion, vs. $2.87 and $102.3 billion. Also after the close today: ServiceNow ($NOW), with options implying about 10.4%, fell after each of its last three reports: 9.9% in January, 17.8% in April and 3.7% in July. Churchill Downs ($CHDN) has alternated direction after its last four: +7.8%, -6.0%, +10.1%, -6.6%. MGM Resorts ($MGM) moved less than 3.5% after each of its last four, and analysts expect adjusted EPS of $0.08 vs. $0.24 a year ago. St. Joe ($JOE) also reports. Before the open Thursday: Cheniere ($LNG) moved more than its 4.0% implied move after three of its last four reports. Hyatt ($H): analysts expect adjusted EPS of $0.77 vs. a loss of $0.30 a year ago. TechnipFMC ($FTI): EPS of $0.88 on $2.79 billion of revenue expected, vs. $0.75 and $2.65 billion. DT Midstream ($DTM): EPS of $1.13 expected, the same as a year ago.

Rihanna has now surpassed 9 billion total streams on Spotify in 2026 so far, despite her last album being released nearly 11 years ago. She’s the 3rd most-streamed female artist of the year and the #1# most-streamed Black female artist.

Here is the arithmetic that the phrase "Global South" obscures: Africa: 1.6 billion people. Asia: 4.9 billion people. Latin America and the Caribbean: 670 million people. Together: roughly 7.2 billion people out of 8.3 billion on earth. The "Global South" is not a minority asking to be included. It is the majority that has been structured out of power. The entire architecture of the post-war international order, the Security Council veto, the IMF voting weights, the WTO rules, the dollar as a reserve currency, was built to ensure that 7.2 billion people would not have proportional influence over the decisions that shape their lives. That architecture is not natural law. It is a set of choices made by the winners of a particular moment in history, encoded as permanent, and maintained by the threat of consequences for those who question it. Questioning it is not radical. It is arithmetic.

BREAKING: Institutional investors bought +$4.1 billion in US equities in the week ending September 18th. This marks their 3rd weekly purchase over the last 4 weeks. As a result, the 4-week average of institutional purchases rose to +$2.9 billion. At the same time, hedge funds purchased +$1.2 billion, bringing their 4-week average of purchases up to +$1.6 billion. Meanwhile, retail investors sold -$2.2 billion last week, posting their 8th consecutive weekly sale. Retail investors have now sold an average of -$1.9 billion in US equities per week over the last 4 weeks. Institutions are buying while retail is selling.