Breaking the mold with #RNA—a# “ #RNAissance# ” of life science. . #RNAtherapeutics# #RNAdrugs# #Oligonucleotides# #mRNAtherapeutics# #mRNA# #siRNA# #RNAi# #Antisenseoligonucleotides# #Antisenseoligonucleotides# #ASO# #NucleicAcids# .

From nucleic acids to real-world impact. OTDC 2027 explores advances in oligonucleotide therapeutics, RNA medicines, and delivery technologies. 📅 May 11–12, 2027 📍 Boston, MA & Virtual 🔗 #OTDC2027# #Oligonucleotides# #RNAtherapeutics# #DrugDelivery#

🧬 From nucleic acids to real-world impact. OTDC 2027 brings together emerging science in oligonucleotide therapeutics, RNA & mRNA medicines, and innovative delivery technologies. 📅 May 11–12, 2027 | 📍 Boston, MA & Virtual 🔗

🧬 From Nucleic Acids to Real-World Impact. OTDC 2027 explores advances in oligonucleotide therapeutics, RNA medicines, and innovative delivery technologies. 📅 May 11–12, 2027 | 📍 Boston, MA & Virtual 🔗 #OTDC2027# #Oligonucleotides# #RNATherapeutics#

LNPs are often typecast as having one job — packing therapeutic nucleic acids for delivery. But that’s a vast oversimplification. LNPs have multiple components (including lipids, polymers, and chemical or protein ligands) and functions, including cargo protection, tissue/cell selectivity, liver detargeting, intracellular delivery, and tolerability enhancement. Co-optimizing all of these components while checking all these functional boxes requires intensive bioengineering. @mirai_bio is leveraging machine learning expertise — informed by enormous, proprietary in vivo datasets — to iteratively develop precise LNPs. This robust design and optimization process creates LNPs that home in on targeted tissues while avoiding hepatic capture. Read more:

Today, we’re launching the Geodesic API Platform. For the first time, Geodesic is making our AI models and drug discovery capabilities available through APIs. At its core is NovaAtom, our in-house model for predicting the structures of proteins, small molecules, nucleic acids, and their interactions. Now available in Lite Preview, this is the first time NovaAtom has been made available beyond Geodesic’s own discovery platform. Alongside NovaAtom, we’ve integrated the field’s core models — carefully curated and continuously updated. To use the API: curl -X POST \ -H "Authorization: Bearer $GEODESIC_API_KEY" \ -F "model=novaatom" \ -F 'params={"jobName":"rbd-nanobody","sequences":">rbd\nTNLCPFGEVFNATRFASV...\n>nb\nQVQLVESGGGLVQAGGSLR..."}' Poll the job, pull the results, and feed them directly into the next model. Your AI assistant can use the platform directly, too. Connect Claude Code, Codex, or your own agent with one URL and an API key. We manage the integrations and handoffs. You focus on the science. Understand biology. Predict structures. Design proteins. Discover molecules. One key. One interface. Start building today!

I am pleased and proud to see OpenAI endorse several California laws currently on Gov. Newsom's desk, two of which are close to my heart: One would authorize independent verification organizations (IVOs) for assessing AI risks, and the other would create the first legislative requirement for screening synthetic nucleic acids. The latter is not an AI policy directly, but is going to be a key part of maintaining societal resilience as AI systems do for biological risks what they have already done for cyber.