New NOVA nanobody target is live: IL-6 (Interleukin-6)
IL-6 is one of the central signaling proteins behind inflammation and immune regulation.
When dysregulated, it has been implicated in:
- autoimmune disorders
- chronic inflammation
- neuroinflammation
- blood-brain barrier disruption
Making it a highly relevant target for inflammatory, neurological, and immune-related diseases.
The IL-6 inhibitor market is already worth billions annually, with drugs targeting this pathway generating multi-billion dollar revenues across autoimmune and inflammatory indications, validating both the biological and commercial importance of the target.
Miners across NOVA will now compete to design nanobodies targeting IL-6 in an open, adversarial discovery environment.
Top submissions may also be selected for wet lab validation through our partnership with
@Yalotein, helping close the loop between decentralized virtual screening and real-world biologics development.
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