We’re announcing that Forus has raised a $150M Series C at a $3B valuation to build the AI network for medicine. Medicine will remain one of the world’s most important industries until humanity achieves immortality, and we are only at the beginning of a new era in what it can do. GLP-1s are changing obesity and cardiometabolic disease. Gene therapies can treat diseases at their genetic source. New cancer treatments are turning diagnoses that were once fatal into diseases people can live with. AI is enabling us to discover of new drugs even faster. But discovery is only the beginning. It still takes more than a decade and billions of dollars to turn a new molecule into an approved medicine, and once it reaches market, more than a third of patients prescribed specialty treatments never receive their first dose. Forus is creating the AI network to accelerate the entire medicine pipeline, from development and launch through prescription and treatment. We connect the companies creating medicines with the doctors who prescribe them and the patients who need them. Today, Forus supports millions of people across all 50 states and is already used by providers to treat patients in 85% of U.S. residential ZIP codes. 9 of the top 15 global biopharma companies work with us, alongside many fast-growing biotechs. Our goal is to put Forus in every doctor’s office in the country and unlock an order of magnitude more medicine for society. There is a generational opportunity to rethink how new medicine reaches people. Forus is becoming how medicine moves from discovery to treatment in America, and as we scale, we’ll become the most important company in life sciences. Forus is not constrained by capital or customer demand; we are constrained by the talent and capacity of our team. To take on the opportunity in front of us, we need exceptional engineers and operators in New York who want to move fast and help us make something that matters. Come build with us. Our Series C was led by Bain Capital Ventures, with Thrive Capital, General Catalyst, Accel, Redpoint, BoxGroup, Pear VC, Vast Ventures, and SV Angel investing alongside them.

Congratulations to @nirzuk , Wilson Xu, Udi Shamir, and the entire Cylake team on their $245M funding round. We're honored to be on this journey with you. Cylake is building a complete cybersecurity platform for full data sovereignty in on-premises and private environments that demand operational control and accountability. By operating on a single, complete data foundation, Cylake closes the coverage gaps that fragmented tools leave behind. This team has a rare depth of experience building the cybersecurity category from the ground up. Nir founded Palo Alto Networks, and Udi and Wilson helped define the modern firewall category alongside him. We're proud to back Nir, Wilson, Udi, and the entire Cylake team as they give organizations a way to adopt advanced security without giving up control. 🎉

Designing a building shouldn't feel like being crushed by one, yet the tools architects rely on haven't meaningfully changed in 30 years. Congratulations to Amar Hanspal and the Motif team for creating a rich, liberating, joyful experience for designing buildings. Motif's agent-native BIM is built for the modern world and instantly connects to every tool and system you use. We couldn't be more excited about this adventure. Congratulations team!! 🎉

Today we're announcing Coder Agent Relay: a new way to give Cursor Cloud Agents self-hosted execution environments on your infrastructure. Launching with @SpaceXAI for regulated enterprises where code can't leave the network. 🔗

Just one day after setting up Revel, an intern at @OrbitalOps_ was already using it to independently run 40 hot-fires. Orbital Operations is developing a high-delta-V, high-thrust rocket vehicle around a first-of-its-kind cryogenic propellant management system to unlock rapid mobility across LEO, GEO, and beyond. Fresh out of @ycombinator Combinator W25, their small team—half of them interns—needed test software that could move as fast as they did. Before Revel, Orbital Ops had never run a test. They had no data recording, no automated sequencing, and no software team to build either. With Revel, they now: • Run dozens of tests in a day • Give interns ownership of entire engine subsystems • Operate five-plus test cells daily, up from a single test cart All without a single software hire. Thanks to @BenSchleuniger, Ross Doherty, @nicosuave9, Dane Patten, @stefan_salaices, and the rest of the Orbital Ops team for the partnership. Link to the full case study in the replies.

𝗧𝗵𝗲 𝗘𝗻𝗱-𝗦𝘁𝗮𝘁𝗲 𝗙𝗮𝗹𝗹𝗮𝗰𝘆: 𝗪𝗵𝗲𝗿𝗲 𝗜𝘀 𝗔𝗜 𝗦𝗲𝗰𝘂𝗿𝗶𝘁𝘆 𝗚𝗼𝗶𝗻𝗴? Frontier AI models had a giant performance gain in coding in the Fall of 2025 Then with cybersecurity in April This is now happening with open-weight models We are optimistic about the long-term But outside of a few players, we believe the world is not ready in the short-term

Today we’re introducing Delta. Delta is a multiplayer environment for coding with agents and reviewing what they build, powered by DeltaDB. The first invites to our private beta are going out now.

Some AI infrastructure buyers are placing multi million dollar orders without knowing the final price. @ericabrescia went on Bloomberg's "The Close" with Romaine Bostick, CFA to talk about Super Micro and the state of the AI infrastructure market. She covers: ◾️ The real logic behind Nvidia's $500 billion financing push ◾️ The shift in how companies are actually using AI models day to day that's changing the cost equation ◾️ Why @poolsideai's new open weight model release is a preview of where AI costs are headed next

Why did a spend management platform start its own AI research lab? @karimatiyeh describes @RampLabs as a “collection of crazy ambitious people that don’t like to be told that something is impossible”. It started about a year ago and has since worked on projects like building its own production-grounded coding benchmark “Ramp SWE-Bench”, putting Claude Code in RollerCoaster Tycoon, and a mechanistic interpretability playground. The Redpoint team spent the day with Ramp Labs to answer questions like: ▪️ How did Ramp Labs get started? ▪️ How do they decide what research to pursue? ▪️ The long-term vision for Ramp Labs

Congratulations to Ankur Singla, Ted Schmidt, and the entire Lumilens team on their $700M Series C at a $5.5B valuation. We're honored to be part of this journey. The bottleneck in AI infrastructure isn't GPUs - it's connecting them. Copper interconnects are approaching their physical limits, and the next generation of AI clusters will require optical interconnects to keep scaling. Lumilens designs and manufactures optical interconnects for both scale-up and scale-out networking. From chip assembly through high-volume production, Lumilens has developed proprietary manufacturing processes and a supply chain purpose-built for high-volume production. Lumilens is already in a rare class of companies capable of delivering at true hyperscaler scale. We're proud to back the Lumilens team as they build the connectivity layer for AI delivery and consumption.

Are Chinese open models being oversold as reaching the frontier? We’re back with another vibe check episode with @arimorcos and @_RobToews. These are a ton of fun to record and this was a particularly meaty one given everything going on. We hit on: ▪️Did Chinese open models catch the US frontier? ▪️How much does distillation explain China's progress ▪️Reactions to Anthropic Backlash ▪️What a Stuxnet style backdoor in model weights looks like ▪️The OpenAI and Hugging Face breach ▪️xAI and Cursor ▪️Prediction check-ins 0:00 Intro 2:41 China's Open Source Models Catch Up 7:42 Does Distillation Explain China's Rise? 13:54 The Geopolitical Risk of Chinese AI Models 20:28 Should the Government Restrict Open Models? 22:06 What Are the Labs Really Learning From You? 29:22 Future of Government Regulation 40:50 The OpenAI-Hugging Face Hack 47:59 Grok, Cursor, and the Value of Real Data 56:52 SSI and OpenRouter 1:02:52 Venture Capital's Return to Deep Tech 1:05:16 Quickfire YouTube: Spotify: Apple:

"As a proprietary model builder, you're kind of starting to get squeezed in.” That's @ibab’s take on where the biggest AI labs stand today. He explains how you need the models to get way better to keep margin, but at some level they may be too sensitive to release. This week, I sat down with Igor on Unsupervised Learning. It was a fascinating conversation with someone who has real perspective on the questions everyone in AI is asking right now. From DeepMind's StarCraft project to early reasoning work at OpenAI to co-founding xAI, Igor has had a front-row seat to nearly every major AI breakthrough. He's now the co-founder of River AI, building individualized, locally-run AI models. We discuss: ▪️Why proprietary model labs might be in trouble ▪️What it's like working with Elon ▪️Building Colossus in 120 days ▪️Should enterprises train their own models ▪️What’s left for humans as models get better ▪️Why he left xAI to bet on personal local AI instead ▪️The three bets River is taking ▪️What's stopping AI from moving beyond coding ▪️Reflections on the rapid pace of the past years 0:00 Intro 1:17 Writing Fiction on Where AI Is Headed 4:46 Cracking Agents Beyond Coding 10:29 Why Igor Left to Start River 12:22 River's Three Big Bets 18:06 Weights vs. Memory: The Personalization Debate 22:04 Should Enterprises Train Their Own Models? 25:10 Are Proprietary Labs Losing Their Edge? 32:16 The China Open-Source Problem 44:19 The Elon Call That Started xAI 50:18 Thoughts on Cursor Acquisition 52:16 What's Actually Bottlenecking AI 56:55 Humans, Machines, and Staying Relevant 1:01:29 Igor's Odds This All Goes Well YouTube: Spotify: Apple:

"Power drives everything in space. It's the fundamental metric that ties every development back to it, from communications throughput to how much compute you can host in orbit." @K2SpaceCo announced a $500 million Series D this week, and co-founder and CEO @KaranKunjur laid out the thesis behind it on @tbpn . The round lands 120 days into the mission of Gravitas, K2's first mega-class satellite, giving the company real-world proof that its bet on building bigger, higher-power satellites actually works in orbit. K2 has now crossed $1 billion in signed commercial and government contracts and is gearing up to build as many as 100 large satellites a year. Congratulations to Karan, @neelkunjur, and the entire K2 Space team on this news 🎉!

We're honored to continue our support of @K2SpaceCo as @KaranKunjur, @neelkunjur, and the entire team close their $500M Series D. K2 is on an important mission to build massive, high-performance satellites across all orbits. These satellites unlock new commercial and government opportunities that will define the future of space. Space is becoming one of the most strategically important technology sectors, and K2 is quickly establishing itself as one of the most innovative teams in this market. They're not assembling a satellite; they're redefining the architecture needed for the next decade of space missions. In just 4 years, K2 has already designed and deployed multiple space technology breakthroughs. Technical diligence in this category is hard, but one of the clearest signals is where the most talented people in the domain choose to go. With K2, that signal was impossible to ignore, and we continue to be amazed by everything this incredible team has accomplished. We're proud to partner with Karan, Neel, and the whole K2 team as they expand the boundaries of what's possible in space. Congratulations 🎉!

The Redpoint InfraRed 100 is now live. These are the companies building the infrastructure that powers everything happening in AI right now, from world models and agent runtimes to the sandboxes, databases, and security tools agents depend on. Congratulations to this year's honorees! Read the full 2026 InfraRed Report: our state of the union on AI and cloud infrastructure 👉