Ruslan Rust(@rust_ruslan):Really cool new model out of the @Sergiu_P_Pasca lab at Stanford. They engineered mice missing most of their cortex and hippocampus, then transplanted human brain organoids into that space. The grafts matured, wired up with the host brain, and even rescued working memory deficits in the animals (now out in Nature). Awesome piece in @TheScientistLLC by Mariella Careaga digging into it, happy to have contributed a few thoughts. Check out the few story here:

Ruslan Rust

@rust_ruslan

Asst Professor @USC with interest in the brain, BBB, stem cells, AI + what can go wrong after stroke & AD. Alum @ETH_en. Fixing science @ResearchHub

Joined June 2019

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Ruslan Rust@rust_ruslan

2026.09.16 16:27

Really cool new model out of the @Sergiu_P_Pasca lab at Stanford. They engineered mice missing most of their cortex and hippocampus, then transplanted human brain organoids into that space. The grafts matured, wired up with the host brain, and even rescued working memory deficits in the animals (now out in Nature). Awesome piece in @TheScientistLLC by Mariella Careaga digging into it, happy to have contributed a few thoughts. Check out the few story here: