My thoughts after daily driving Silico:
It makes research substantially more joyful and exciting, allowing me to accomplish more and explore a more diverse set of methods and ideas. It's sticky; I don’t want to go back to not using it. The agents have more freedom and agency than in Claude Science. Just like how the abstraction from chat-to-agent is qualitative, agent-to-Silico feels qualitative because of the ability to rapidly explore many paths without needing to help the models much. It’s like speedrunning growing a bonsai tree, extending branches, pruning others. I tried Silico on both genomics and mechanistic interpretability. Also, tell me what I should try next
Before Fable was locked in federal prison, they made a new type of spline designed to fit extremely high dimensional (e.g. 30D) objects. Currently benchmarking it to see if it's good