Andrew Aiginin
@andrewaiginin
AI-ginin. All in AI 🤖 Generative Biologics product manager at @InSilicoMeds. Whatever I post here reflects my personal opinion.
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GPT-6 Astra is now the best-performing frontier model for antibody developability prediction in our benchmark. 🧬
Finding an antibody that binds is only the beginning. Will it aggregate? Will it stay stable? Can it actually behave like a drug?
GPT-6 Astra predicts these developability properties better than the other frontier models we tested. 🤯
And yes, the interactive visualization showing how an antibody actually works was also built with Astra in about 1 hour.
This model looks seriously powerful.
Congrats @gbt @sama
#insilicoSOTAFM#
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Yesterday, I built a cell model. 🧬 Today, it showed me how Ozempic works.
I asked it to explain the mechanism.
1 hour later... THIS. 🤯
GPT-6 Astra is insanely powerful. 🚀
I can’t stop @DeryaTR_ @gdb
Now I’m wondering... can it model the rentosertib mechanism? 👀
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We should understand that neither Claude Opus nor Mythos themselves designed those binders. They used specialized models for this, and these are normal hit rates for BindCraft or Boltzgen, especially for previously seen proteins that have appeared in articles and competitions along with the binders.
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