My perfect Sunday morning: Wake up at 6:00 AM. Get my coffee. Jump into Codex. Launch Live Voice (a.k.a. Jarvis). Discuss and plan with it the next immune/cancer app. Tell Jarvis to start building. Save the world!

I’m super excited for this Builders Unscripted podcast with @romainhuet at @OpenAI. He is a fantastic interviewer & the talk flowed so naturally, completely unscripted! This was also mostly about Codex & how I've been using it in building biomedical apps, with some real demos! ☺️

I’m very excited about this article from @OpenAI on my attempt to use GPT-5 Pro to understand the results of an experiment we did several years ago. Remarkably, GPT-5 Pro figured out the key mechanisms, as explained in the article & infographic below!

Some people are defending Anthropic despite everything that is happening, largely because Fable 5 is an amazing coding model. I can confirm this is true, and I do not think anyone would seriously argue against it. Even its high cost should not be an issue. We live under capitalism, and companies can charge what the market allows. But, and this is a very big but, there is a much more important issue here. What these people do not understand is that Fable will be the best coding model only for a short while. Others are very close behind. In fact, even better models will arrive soon, and coding itself is clearly on the path to being largely solved. Models will then become cheaper over time. If you do not get to build your amazing software a few months earlier, that probably will not change much in the world. At most, it may delay your personal ability to benefit from it for a while. It might even benefit you, by saving you from wasting money and time before better and cheaper versions arrive. But a doctor cannot wait to treat patients. A scientist trying to cure cancer does not have the luxury of waiting months. Every day of delay in research and clinical applications costs lives, potentially thousands of them. Every day that scientists around the world are denied access to the best models is another day the world is delayed from becoming better. And this is not only about model access. Anthropic has also advocated for pauses and regulatory capture. They are strongly against open models. In my view, this is not driven by some pure concern for humanity, but by the fact that such control would give them more money, more power, and more leverage over the future. Therefore, I believe it is far more important to be principled and stand for humanity than to chase short-term personal benefit. That is the reason for my outrage against Anthropic. It is nothing personal against poor Fable 5, or against the great AI engineers at Anthropic who are building these models. I do not doubt that many of them are sincere, and I am grateful to all frontier AI engineers who are pushing this technology forward. But I do hold those in charge of Anthropic responsible. Their founders and leadership should be held accountable for what I see as self-serving and deeply misanthropic actions. I also do not think they care. Not one of them has meaningfully responded to the outrage. This is also a note to everyone who keeps claiming that AI itself is the threat to human existence. No. It is not AI itself. It is the humans who control AI who may become the real threat to humanity, as I have said repeatedly. We have to resist this power capture at all costs, if we truly care about the rest of humanity.