Anuruddh Mishra (@anuruddh_m)

2026.09.22 21:10

This is a really interesting way to think about ADHD. A substantial subgroup of people with ADHD appear to have a delayed circadian rhythm, with later melatonin onset and delayed sleep timing. The 2025 paper by Luu and Fabiano pulls together evidence that shifting the body clock earlier with things like morning light, consistent wake times and in some cases melatonin may improve ADHD symptoms, although much of the intervention evidence is still early.

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Anuruddh Mishra@anuruddh_m

2026.09.22 20:50

This is where agents could really change healthcare. So much of the market is fragmented that better matching is a much bigger unlock than it sounds. Agents can make those connections without everything needing to fit into a perfect taxonomy.