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Fabrizio Serafini
@fabrisera2000
Investment Partner @a16z - AI Apps. @Harvard Stats and CS.
373 Following    151 Followers
Thrilled to be partnering with @MoOueida and the team at @StitchHQ to build modern AI native infrastructure for financial institutions across the GCC and beyond. Also proud that this is @a16z’s first investment in KSA.
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There’s a been a lot of talk of what’s durable in software in headless agentic world and where the opportunities are - we made a scorecard 📋 👇
Thrilled to have @lloydblankfein join me on the @a16z podcast. Lloyd is arguably one of the most effective and resilient leaders Wall Street has ever produced. Having joined @GoldmanSachs in 1981 and rising to Chairman & CEO from 2006–2018, he skillfully guided the firm through the 2008 financial crisis—transforming it into a bank holding company and positioning it as a dominant global powerhouse while many competitors faltered. This was a particularly fun and wide ranging conversation as Lloyd shares his story of growing up in the projects in Brooklyn, getting into Harvard, joining Goldman via acquisition of J.Aron and rising through the organization as a creative trader and risk manager. We touch on the opportunities and risks he sees in AI and what young people should do to build a successful career. Hope you enjoy this conversation with Lloyd!
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Claude code is extremely good at HTML - only nit is that it often generates multi thousand line files rather than breaking them down like a human would. Still - pretty impressive
Think there’s so much discussion around Anthropic vs. startups, but think much more interesting discussion should be around market expansion enabled by AI across the board. Sure there’s going to be some losers but the big picture is very promising and not zero sum at all
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FDEs are going to be coming in to commercialize the LLMs. This means startups will experience competition. Is this a bad thing? No, it means startups have to compete harder and smarter. Time to make better software, software an FDE at the labs can't make.
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Will Smith eating pasta is now the official benchmark for AI progress. This is actually insane.
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Tesla Vision allows us to deploy airbags up to 70 milliseconds earlier if your Tesla detects an unavoidable collision This can be the difference between serious injury & walking away from a crash
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Life update: today is my last day at @insightpartners Hard to overstate what these years have meant to me. The gift Insight gave me is agency - the freedom to explore, build, and break things. I got to grow as an investor and build agentic systems at the same time, in the same place - that combination is rare. Feel lucky to be doing this work in a moment like this - a sci-fi era where computers can talk back, think with us, build with us. What a time! Matt, Max, Byron, Alessandro, Max, Hugues - thank you for betting on me, taking me under your wing, and shaping how I think. You are the firm. To the founders I've worked with: you are the most relentless, optimistic, brilliant people I know. Thank you for letting me into your stories. Building is a long game - I'm in it with you. Arrivederci, Insight!! What's next: more soon 🙌
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Husband and Claude set up a receipt printer to make daily briefings for the kids
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Live from Code with Claude: we're launching dreaming in Claude Managed Agents as a research preview. Outcomes, multiagent orchestration, and webhooks are now in public beta.
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Tony James is arguably the best investment firm builder on the planet. Having scaled DLJ to the largest alts platform in the world when it sold to Credit Suisse, and again with Blackstone from $14B to nearly $1T in AUM. Along the way he just happened to lead the Series A into Costco (and Starbucks!) in the 1980s (and has been on the board ever since). What is equally striking to Tony's success is the incredible impact and legacy he's had on the people he's worked with over the years. Some of the most successful people in finance credit their careers to Tony's mentorship / guidance. I hope you enjoy this conversation as much as I did.
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Unpopular opinion: "AI makes everyone a developer" is true the same way "cameras makes everyone a photographer"
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We have been testing GPT 5.5 on the hardest spreadsheet tasks in the world (100k-1M+ cell complex models). It is the Pareto frontier for spreadsheets -- SOTA accuracy, the fastest and the most efficient public model across effort levels. OAI really cooked here
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✅ Claude Code ✅ Claude Cowork ✅ Claude Design 🔲 Claude Marketing 🔲 Claude Sales 🔲 Claude Finance 🔲 Claude HR 🔲 Claude Operations 🔲 Claude Customer …
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Welcome to Pillar - your Agentic Global Risk Management department. Hedge your commodities risk in real-time, all in one platform. If you are a manufacturer exposed to commodity risk, couldn’t be a better time to check them out. Congratulations to @harshavramesh and his incredible team!! 🚀
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The world is fragmenting. Supply chains are shifting. Volatility is no longer cyclical - it’s structural. Yet most businesses still manage risk on spreadsheets and phone calls. In a world of tariffs, wars, and supply shocks - that doesn't hold up. Markets move too fast. Today we’re publicly launching Pillar, and announcing an additional $20m in investment, led by @a16z. Pillar is an AI copilot for commodity and currency hedging - built for real world operators like you. We monitor your physical exposures and manage risk in real time - protecting your margins at all times. If you operate a physical business, let’s talk!
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Introducing Claude Managed Agents: everything you need to build and deploy agents at scale. It pairs an agent harness tuned for performance with production infrastructure, so you can go from prototype to launch in days. Now in public beta on the Claude Platform.
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We released Claude Opus 4.6 just two months ago. Today we're sharing some info on our new model, Claude Mythos Preview.
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