Oligonucleotide scientist
@Oligonucleoti20
Experienced Oligonucleotide scientist. Possess strong R&D expertise in nucleic acid chemistry.
716 Following 245 Followers
RNA biotech startup Switch Therapeutics nabs $52 million in financing backed by UCB Ventures, Eli Lilly, others
Scopus BioPharma (Nasdaq: $SCPS) is pleased to announce the FDA approval of the IND application for the company’s lead drug candidate - a distinctive RNA therapy and immunotherapy.
Read more here:
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Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents
$BEAM #CRISPR# $NTLA $CRSP $SGMO $EDIT @GaetanBurgio @monicazwu @CRISPR_papers @liugroup @ESontheimerLab @NicoleGaudelli
@KomorLab @JKeithJoung @JulesGrunewald @zhangf
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REVIEW: Recent progress in non-native nucleic acid modifications
@F_ANAtico @DamhaLab @Hollensteinlab
@IS3NA @arseniyadis @mmckeague @Oligonucleoti20 @hocekm @PhilHolliger @KitchenChemProf @FakihH9 @Leonora_Abd @RNAVarley @MokhirG @DrMikeBooth @LucksLab
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After nearly two decades of research & development, our community celebrated when the first siRNA-based RNAi drug gained approval. Read on to learn about key milestones in the discovery & development of siRNA.
#rnai# #sirna# #oligotherapeutics#
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BREAKING NEWS:
The 2020 #NobelPrize# in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”
Delivery of Oligonucleotides to the Liver With GalNAc: From Research to Registered Therapeutic Drug - PubMed
We are getting enthusiastic feedback & questions about our partnership with @ProjectALSorg to fund a #ALSresearch# project for jacifusen. This study is part of a larger strategy to ensure everyone with #ALS# has access to effective treatments. Read more:
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Structure of novel coronavirus spike protein solved via @cenmag
"When I draw a molecule in China or in Argentina, it is the same molecule. People understand immediately without knowing Spanish or Chinese. That is beautiful. Our common goal is not about power or borders of the country, it is about bringing forward human knowledge." Ben Feringa
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N-of-1+ oligonucleotide therapeutics are becoming available for more rare disease patients!
Of all platforms for drug devt., only oligos are feasible to cost-effectively treat unique mutations.
Pharmacokinetics of Patisiran, the First Approved RNA Interference Therapy in Patients With Hereditary Transthyretin-Mediated Amyloidosis
$ALNY @JMaraganore @Alnylam
$DRNA $ARWR $ABUS $RXII $SLN $AMGN @OliXPharmaceut1 #siRNA# #RNAi# @RNAi_papers
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FDA approves Alnylam’s Givlaari, second-ever drug based on RNAi via @statnews @OTSociety @IS3NA @jwattsgroup @DamhaLab @JP_Desaulniers @NSERC_PROMOTE
Congratulations Laura! @LauraSepplore
2019's Fiercest Women in Life Sciences
Roche signs up Dicerna in a $200M-plus cash alliance to help develop a hep B cocktail, capping biotech's big year
