this might be my last normal tweet before biotech goes vertical i'm not a whistleblower. I don't work at Lilly, Novo or any of the big labs but there is a massive shift happening in human biology right now. it's sitting in press releases and almost nobody reads them the last 6 months alone: - a once-daily pill roughly doubled median survival in metastatic pancreatic cancer (13.2 vs 6.6 months) - a one-time gene editing infusion cut hereditary angioedema attacks 87%, and 62% of patients stayed attack-free and off all other prevention for 6 months - a one-time gene edit for cholesterol dropped LDL up to 62%, and it held for over a year - a personalized mrna vaccine beat keytruda alone in a 1,137 patient melanoma phase 3 - retatrutide hit ~28% weight loss in a phase 3 - an ai-designed drug entered phase 3 - a pill that regrows hair passed its second phase 3 - an immunotherapy that could let some rectal cancer patients skip surgery, chemo and radiation just got fda approved - a man lived 271 days off dialysis on a pig kidney - human cells were caught passing chromosome-sized chunks of DNA to their neighbors, and it changes how the neighbors behave we are on the verge of an era where the human body is a software problem and the update cycle gets shorter everyday stick around, it's going to get weird bio/acc

cancer treatment in 2025: find the tumor, cut it out, poison the rest with chemo, hope the patient survives cancer treatment in 2026: sequence the tumor's DNA, identify the exact mutations driving it, design a treatment built around those mutations specifically, train the patient's own immune system to hunt them down it's coming fast, bio/acc.

AI will be safer than human doctors this year. I spoke to Superpower founder @maxmarchione on why health is an information problem a human brain can't solve, and why half of humanity will be on a daily peptide within 10 years. 00:00 - Health Post AGI 04:04 - Healthcare Is Broken 07:14 - Execution Is The Moat 10:29 - The Tesla of Healthcare 14:23 - AI Caught a Stroke 19:45 - Apple vs OpenAI 23:23 - AI Doctors = Driverless Cars 26:02 - Truth-Seeking Medical AI 30:26 - Are Biomarkers Irrelevant? 33:37 - Doctors Can’t Think 36:18 - Peptides for All 40:19 - What Are You On?

longevity clinic in america: minimalist waiting room, $1,200/month subscription, 47 page protocol, a nutritionist named Sage explains your "cellular wellness journey," biological age comes back the same as last quarter longevity clinic in an unmarked building in Shenzhen: guy named Wei doesn't smile once, hands you a vial, says "come back in 6 weeks," charges you $80, biological age actually drops by 4years wtf