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Nick Mark MD
@nickmmark
Intensivist | Husband, Dad² | created the #1# critical care podcast @CritCareTime & infographic site @OnePagerICU | passionate about MedEd & MedTech innovation
1.6K Following    69K Followers
The right-wing Anakin posting does make a lot of sense as it combines many of the Right’s core preoccupations: getting groomed; killing your wife; working for an insane, octogenarian tyrant; being hated by your children; losing and dying
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You cannot fire scientists, halt ongoing research and clinical trials, drive away the next generation and then declare a “golden age” of American science. These cannot fundamentally coexist. As we head into the elections here is a breakdown breakdown of the damage done to the U.S. scientific ecosystem so far: Defense research labs lost roughly 14% of their staff. The Pentagon itself warned of “potentially grave consequences for the future of national defense.” NIH staffing fell by 1/5. More than 2,000 biomedical research grants were delayed or canceled, affecting work on cancer, Alzheimer’s and other major diseases affecting the health of American public. HHS announced a wind-down of mRNA vaccine development at BARDA, affecting 22 projects worth nearly $500 million through cancellations, cuts and restructuring and halting new mRNA projects under the program. The National Science Foundation lost roughly 1/3 of its staff and withheld more than $1 billion in funding. The Energy Department lost more than 1,000 scientists and technical staff. Grant awards from its two major science offices fell by more than $500 million during the administration’s first year. NASA lost 20% of its employees with Ph.Ds. Foreign Ph.D. applications at leading universities fell 21%. Schools reduced admissions as funding uncertainty made it harder to support future scientists and removing a pathway for sustaining scientific excellence globally. Meanwhile, a proposed rule would give political appointees greater control over who receives research funding, screening applications for supposedly “anti-American values.” Thankfully Congress rejected the massive proposed budget cuts and courts forced funding restorations. But neither can replace the time and investment already made. We can’t just simply flip the switch back on. And while the federal government can still spend roughly $200 billion on research - we continue to witness the dismantling of the capacity to turn funding into discovery. And make no mistake - other countries are happy to step in - including China - who are recruiting the talent we are losing. The treatments we will need in 20 years depend on the research we conduct today. So do our security, our prosperity and our ability to maintain our lead globally. Vote tomorrow because science depends on it.
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Writing this in my personal capacity, but I have been flying these types of aircraft for more than 20 years, with over 8,000 hours, and have reasonable familiarity with how the charter world operates. I feel compelled to post after seeing commentary about the Lear 60 crash, from missile strikes to DEI to critiquing this poor woman’s final radio calls. That last part is what I find most troubling. She was the second-in-command (SIC), and while she was empowered to point out mistakes as part of good crew resource management, she was doing her job, communicating with ATC right to the end in a terrifying situation. She likely knew before many of those calls that she was going to die. I have heard final calls from friends, from military pilots with thousands of hours in fighter aircraft, and they are just as heartbreaking because they know the end is approaching. I understand the public interest given the footage and audio. But you do not know the aircraft’s maintenance history, whether there was a structural failure, if any failure was induced by turbulence, overspeed, or overcontrol, or everything happening in that cockpit. I am sure weather will be part of the investigation, but beyond that, it is speculation. The charter industry routinely hires commercial pilots very early in their careers to gain experience alongside an ATP-qualified captain before they move up to the airlines. She would still have the appropriate training, qualifications, and checkouts by an FAA examiner or designee. Let people investigate, learn, and share the facts. Be respectful to those who perished and the families who carry their memories. God bless them and their loved ones.
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This is terrifying
If a nuclear weapon were used on Pick Axe mountain in Iran by the US or Israel or an empty field in Ukraine by Russia etc, it doesn’t matter, it would open up Pandora’s box and would make the U.S. and the world dramatically less safe. This isn’t even a question of how big of a disaster the use, in any manner, of a nuclear weapon would be. It would represent the largest foreign policy error ever by the United States if we were involved. We can only hope this claim isn’t accurate in any way.
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A person in Yakima County has died from complications of bird flu following exposure to infected dairy cattle and a 3rd case has been identified. We have too often treated bird flu as a threat we can dismiss. Yet it persists. The reported risk to the general public remains low, but that cannot become an excuse for complacency or for overlooking those whose work places them at greater risk. We need sustained surveillance, transparency, and protection for exposed workers. People need our attention to be protected. The measure of preparedness is whether we act before someone else’s loss becomes the reason we finally care.
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🆕 ICUOnePager on Central Venous Pressure (CVP) monitoring. CVP is not useful for fluid responsiveness but the trend and the waveform can provide many physiological insights! The central oxygen sat (ScvO2) can also provide clues. 1/
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Trump is dismantling the science system that made America a superpower. NIH has delayed or canceled over 2,000 grants on Alzheimer’s, cancer and more, NSF is withholding more than $1 billion, Energy lost over 1,000 scientists, and Pentagon labs lost 14% of their staff, which the Pentagon itself says could have grave consequences for defense. China is catching up while foreign Ph.D. applications drop 21%. We built this over 80 years, and it’s being gutted in under two. #MedSky# #LawSky# #press# #Science# #NIH# #NSF# #Research# #DOGE# #China#
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Or you could just not be a shitty person.
I have this great idea for a drug called Regretamine. One dose and all your regrets are gone! Including, obviously, having taken Regretamine in the first place.
🆕💥🟢Pragmatic cluster-randomized crossover trial in six medical intensive care units Adding 0.12% chlorhexidine to a standardized oral-care bundle did not reduce VAP incidence density or 28-day mortality and was associated with a modest increase in ICU length of stay😲 #IDXposts#
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The people who supported holding 21 hearings about Benghazi are oddly silent about this.
Iran strikes damaged or destroyed US air defenses, aircraft and buildings on over two dozen Mideast bases, an AP analysis finds.
🆕 ICUOnePager on Central Venous Pressure (CVP) monitoring. CVP is not useful for fluid responsiveness but the trend and the waveform can provide many physiological insights! The central oxygen sat (ScvO2) can also provide clues. 1/
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Calling your tour Come and Take It and then retreating from the Alamo is the funniest possible thing this man could do
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Musk’s clumsy incompetence in action: trying to help the GOP he suspends the wrong Dan Sullivan. Free speech moron strikes again.
Trump ordina al DOJ un’azione legale perché un candidato indipendente al Senato in Alaska, Dan Sullivan, è omonimo di quello repubblicano. Elon Musk per supportare Trump fa sospendere Dan Sullivan da X. Ma per sbaglio sospende il Sullivan repubblicano IO-NON-CE-LA-POSSO-FARE
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Alexa please describe in detail how a literal monster would parent his children
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Free speech absolutist also father of the year.
It’s almost like people trained to think critically are less likely to fall for MAGA talking points…
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In medicine we say “recommendations as per our prior notes; thank you for this interesting consult, signing off”
Huge drop in Google searches for various health disinformation topics following the Ukrainian strikes on Russian data centers. It makes you wonder how much of the “turbo cancer, ivermectin” nonsense is really fueled by Russian bots, & how many Americans they’ve killed…
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An alternative hypothesis: - model performance is plateauing - compute is getting much more expensive - AI data centers are massively unpopular - slowing down AI development is a way to explain slowing progress, reduce spending, and try to regain some goodwill. - This is an effort to save the IPO not humanity.
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