Some super nuance here from a neurosurgeon: She almost certainly was not misdiagnosed. At the time, IDH mutation was not the distinguishing determining feature for WHO for what gliomas were/weren't GBMs. That being said we've known for twenty years that IDH1/2 mutations are super important in prognosis. But other things greatly influence prognosis as well - age, EOR, MGMT status, etc Obviously there are no details here on her talks with her care team. But prognosis in cancer is quiet difficult to communicate. Patients have just been hit with a train and trying to have some nuance around long tails, distributions and median survival can get comrpessed into "you have X months to live" even when communicated well. Ideally humans need to be presented complex information like this MULTIPLE times to fully grasp it. But these conversations are hard and often times with different providers and so discussion of prognosis, especially early in a cancer diagnosis, at least from personal experience, can be very one and done. Even if her IDH status and MGMT status and what it meant was communicated it may not have been done enough. Or maybe it wasn't at all and that's something of a failure. But its not like ChatGPT fixed a misdiagnosis.