This week in SF with award-winning filmmaker Darren Aronofsky @DarrenAronofsky, @openai researcher Noam Brown @polynoamial, and Dylan Golden president of Primordial Soup We discussed the future of filmmaking, building creative models, and Hollywood and Silicon Valley’s long partnership & recent tension Put on the by the one & only @eladgil, & @emmzaoui

"We have this long term vision of turning biology from something which is trial and error and experimental and make it something that looks more like an engineering discipline in the next century." New Episode with @jackdent ! 0:00 Intro 02:28 Inside @stripe w/ @patrickc, at <100 People 08:45 @sama role in @chaidiscovery origin 16:20 Chai-2 Antibody Breakthrough 19:24 Approaching biology as an engineering problem 24:45 Using AI models to treat people on an individual scale 26:52 Robotics in labs 27:22 Pharma industry today 29:49 The clinical trial bottleneck 32:53 Personalized biology models & cancer vaccines 36:24 Longevity, peptides, and trillion-dollar drugs 39:02 Does it matter that the government cut exploratory science grants? 41:00 What next-gen Chai models will do 42:08 Can frontier AI labs build this themselves? 43:26 Biology is hard