Neal Khosla
@nealkhosla
I judge myself on what my 8 and 80 year old selves would think.
CEO of @CuraiHQ - making healthcare available and affordable to everyone
1K Following 36.4K Followers
*whispers*
Astra is better than Muse for all the same use cases.
1/ We started @CuraiHQ with the mission of proving AI could outperform humans at the core cognitive work of medicine.
Today in @JAMA_Current, @ZekeEmanuel, @AbeBakerButler, @vkhosla, and I are publishing a comprehensive argument this future is here.
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When I was at Google, someone on my team said that when he joined Google pre-IPO 60% of the codebase was written by @JeffDean and @Sanjay_Ghemawat.
That’s the level of legend of these two.
The Friendship That Made Google Huge. Coding together at the same computer, @JeffDean and @Sanjay_Ghemawat changed the course of @Google and the Internet.
Big news!
We are excited to announce our $310 million Series B financing, led by @khoslaventures, with continued support from Andreessen Horowitz (@a16z) and @Breakthrough Energy Ventures, and new participation from Greenoaks, Halo Fund, Pax Ventures, StepStone Group, BHP Ventures, Washington Harbour Partners, Greycroft, General Innovation Capital Partners, Mitsubishi Corporation, In-Q-Tel (IQT), and Earthshot Ventures.
Demand for critical minerals continues to accelerate across every major industry, and building a vertically-integrated company focused on end-to-end autonomy, speed to market, and lowering costs is the only answer to meet the challenge. Our Series B is another crucial step in building the mining company of the future, today – and we’re not waiting to get started.
Read more:
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Total narrative violation for the world models crowd.
This was one of those impressive AI thresholds for me. I gave GPT-5.6 Sol in Codex control over my computer, and asked it to win the daily challenge for the game Slay the Spire 2 (randomized factors, so can't cheat).
It worked for 5 hours, making complex game choices... and won.
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Some fun charts:
1. Each US generation is wealthier than the last.
This was always going to be the case and continues to befuddle that “sophisticated” investors think proprietary data will help.
That’s only true in very specific areas.
But the marketing value of domain specific data still matters to end customers.
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For medical information, general AI frontier models (Google, OpenAI, Anthropic) outperformed specialized @openevidence and @UpToDate as assessed by 12 US clinicians, randomized and blinded to which model and extensive testing/benchmarks. This was not anticipated. @NatureMedicine
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All the glp-1 results are obviously amazing but it’s stunning how many people are surprised to see that fixing your metabolic health has insanely beneficial spillovers to every other area of health
sakana is incredible
For over a decade, we’ve accepted that end-to-end backprop is the only way to train deep networks. But holding the entire network in memory all at once is why AI training is hitting a resource wall.
We found a new way to break the network into blocks and train them independently. The trick? Treating the network’s forward pass like a diffusion model denoising a signal.
This reinterpretation slashes the memory needed to train deep models. In our #ICLR2026# paper ( we matched end-to-end performance across ViTs, DiTs, and LLMs. We did this while training just one isolated block at a time.
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The LeBron James of venture.
All the guys on the 2001 list are retired or irrelevant and here he is at the top again. What a beast.
Then Kleiner Perkins partner Vinod Khosla clinched the top spot in the 2001 list for savvy investments in internet networking startups like Juniper. He again ranks highly for his "foolhardy" 2019 bet on OpenAI among others
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ACCESS is a brilliant idea and the payment rates are more than good enough.
Anyone complaining about it is doing so because they have a model set up for yesterday's technology and payment models.
They either don't want to get paid less or they can't lean on technology enough.
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this is bizarre because jensen is saying out loud that he is demand constrained which is not in line with anything the company has said publicly
his answers around the china issue between dwarkesh and this have been so bizarre i honestly don't know how to react
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*New Lecture*
Stanford @frontiersystems '26, Session 8
The Compute Behind Intelligence with Jensen Huang from @nvidia
full link in comment - this clip is just the one where he talks about tomatoes
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One of the strongest entrepreneurs I know and a great company being built.
Today we’re introducing Forus and announcing $160M to build the foundation for modern medicine.
Science should be the only limit to medicine. Today it isn’t. Drug discovery is moving faster, but the system that turns it into real-world treatment isn’t.
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One of the best digital health companies I know is growing insanely fast and looking for someone to come in and help spread AI throughout the whole org.
