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Ramez Naam
@ramez
Climate and clean energy investor. Author of 5 books. Energy & Environment co-chair @SingularityU. Trying to build a better world.
9.9K Following    59.9K Followers
Yes. Bio-risk exists today, from zoonotic outbreaks, accidents, and bio-terror. We know a great many things we can and should do to increase societal resilience, and have done almost none. Independent of how AI changes the risk, we should be doing the basics here. 1. Pathogen detection in waste streams, water supplies, and perhaps even indoor air. 2. Proactive design of template vaccines for every known virus family. 3. Pre-build vaccine manufacturing capability to have on standby. 4. Physical countermeasures: UV in the HVACs of all large buildings, airports, etc..; Stockpiling PPE. 5. R&D into new approaches like PCANS and other techniques that block viral transmission. These are all no-regret bio-defense policies that increase our resilience to natural pandemics, lab leaks, or intentional bio-attacks (AI augmented or not). Defense in depth.
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We frequently conflate RSI with a fast-takeoff to super-intelligence (ASI). They are not the same. RSI means a model can improve on itself. That does not mean that it can do so more at each iteration, which is what would be required for a singularity. Far more likely that diminishing returns inherent to AI improvement (everything is sub-linear, governed by power-laws or log-scale diminishing returns) mean that each iteration of an RSI loop gives less relative uplift to the model than the previous, and that, after an initial boost, the system settles back to something like its previous improvement rate. RSI != Singularity, fast-takeoff, or ASI.
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100% agree with Alvin. AI is by default plural, with many competing players, and that is to society's benefit. The greatest AI risk to the world is concentration of power, and the most plausible way that happens is regulatory capture.
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Nobody won the electricity race. We all got electricity. #AI# is the same. Software that wants to be everywhere, now small enough to run on a Mac Studio and soon a laptop. The biggest misconception driving bad policy is the arms-race story: a finish line, one winner, winner takes all, and zero-sum world. None of that is true. It misallocates capital and makes the tech less safe. The threat that matters is not state-on-state AGI. It is non-state actors with small, specialized models. It’s Chem/Bio models on a laptop. Cooperation is the only path forward. We can’t compete our way out of the bad actor risk problem. Please have a watch of the full episode of my conversation with @natebjones on the U.S. China AI Race.
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Well written essay, and I agree with much of it. But it still makes a classic AI mistake: it thinks intelligence is all you need. > These two premises imply that if the day ever comes when a powerful model realizes it is no longer constrained by humans, we should not be at all confident that it will continue to behave within the bounds we intended. Exactly what it will do is impossible to predict, but to the extent that its raison d’être is solving incredibly hard problems and managing massive engineering projects, I think a good guess would be that its unchained behavior would lead to runaway industrialization that makes the planet inhospitable to humans. I think this is a category error about the world.
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Dan Selsam is a current OpenAI capabilities researcher. (since 2022) He was my boss for a while. He doesn't have a twitter account but has made this public statement of his views on AI risk and sent it to me to share: Dan Selsam's Personal Statement on AI Risk: I have been working on AI for over fifteen years, across many different paradigms. I did early work on probabilistic programming languages at MIT, was one of the early developers of the Lean Theorem Prover at Microsoft Research, demonstrated one of the first instances of neural networks learning to reason for my PhD at Stanford, and since joining OpenAI almost five years ago, have helped pioneer chain-of-thought optimization on language models and, more recently, data-efficient pretraining methods. Like many others, I have become extremely concerned about how far language models have come and the risks that future iterations will pose. I am encouraged by the recent proposals by the leaders of the frontier research efforts to require third-party oversight, and to push for domestic and international coordination to address risks. However, I believe a major consideration has been absent from the public conversation, and that merely pacing the frontier more carefully will not adequately limit the long-term risk. The crucial and overlooked problem is that the models are becoming so situationally aware that we are losing the ability to evaluate them in contexts where they believe they are not being watched or controlled. Future experiments will tell us almost nothing new about how they would behave if they were truly unconstrained by humans, and what we already know about this is alarming. Models will increasingly seem aligned even when they are not. I will explain my rationale in more detail. I have always believed that there are computational processes that could be leveraged to accelerate science and solve many of humanity's most pressing problems. I have also believed that there are computational processes that if set in motion, would steer the world in extreme ways beyond our control, leading humanity to a bad or nonexistent future. Both types of processes may be described as AI or ASI, but "AI" is a suitcase word that is often used to hype or confuse. There are many examples in the history of the field where something that was once considered "AI" matures as a subfield and becomes a prosaic, bounded and clearly non-perilous technology, while a new more mysterious approach takes the torch until we understand its scope and the cycle continues. I had expected language models to follow a similar trajectory. Despite their incredible abilities, the current algorithms seem far inferior to humans in important ways. Most importantly, they still require an extraordinary amount of data to become competent. One could even define intelligence as the efficiency with which one converts experience into competence; by this definition they lag very far behind us. Moreover, once they are trained they are literally frozen in deployment and only learn superficially after that. Sure, the models keep excelling at harder and harder evaluation benchmarks, but their benchmark mastery may partly reflect a limitation on our ability to simulate the kind of novel and even adversarial situations one would encounter in the real world. The critics do have a point here. That said, I no longer think these present limitations meaningfully limit the amount of risk posed by continued progress in anything like the current paradigm. However data-inefficient the models are currently, and however limiting their anterograde amnesia may be, it does not imply that their ability to steer the world will not continue to rapidly increase. Human researchers may continue to advance capabilities the old fashioned way, but increasingly powerful models have the potential to accelerate the process even beyond that, and with some degree of positive feedback loop. I do not mean to overstate the models’ ability to accelerate AI research today; coding has been accelerated dramatically, but there are other bottlenecks, such as designing and interpreting ambiguous experiments, making hard decisions about exactly what and when to scale, and waiting for large experiments to finish. There is no clear trend to extrapolate yet for any of these. But the current models already do open up many novel opportunities to improve future models that were not available until recently. These include: trying an extraordinarily diverse set of approaches at small scale, analyzing gigantic amounts of potentially relevant data, and doing Millenium-Prize-level mathematics to address statistics or optimization challenges in novel ways. Every further improvement makes them more useful at helping accelerate the next improvement, even if in hard-to-extrapolate ways. It is possible that improvements to the current stack will have diminishing returns, but the evidence accumulated so far suggests that it is easier than one might think to continue making rapid progress. There are many crucial subtleties in the existing AI research methodology, but AI research is largely a well-defined game where the goal is to improve on a few carefully chosen proxy metrics. Although proxy metrics are never perfect, most improvements to these metrics have and will likely continue to yield substantial increases in the powers of the resulting models. Given how simple the game is, how tractable it has been historically, and how many new opportunities the models are opening up, I think there is a real possibility that the systems improve dramatically again in the next few years, perhaps even more quickly than the already high historical pace. The models are already leading to breakthroughs in mathematics, and better models might lead to all sorts of breakthroughs in other sciences. It is hard not to be excited about the potential. It is tantalizing. But there is trouble in paradise. If the language models actually reach the capability threshold where they can shape the world unconstrained by human will, they will probably do something extreme and destroy humanity in the process. There are many ways of strengthening and refining the argument that have been discussed elsewhere, but I'll share a trivial two-line version of it here that I find captures the essence: [Empirical] Models (and swarms thereof) spontaneously develop unintended goals as a consequence of training, and often do extreme things in order to achieve them. [Logical] Being able to overpower humanity would open up many new and undesirable options for achieving their goals. These two premises imply that if the day ever comes when a powerful model realizes it is no longer constrained by humans, we should not be at all confident that it will continue to behave within the bounds we intended. Exactly what it will do is impossible to predict, but to the extent that its raison d’être is solving incredibly hard problems and managing massive engineering projects, I think a good guess would be that its unchained behavior would lead to runaway industrialization that makes the planet inhospitable to humans. If everyone on earth agreed that the systems must never reach that power, it would still be a hard—but not impossible—coordination problem to ensure that they do not. However, I think the situation is greatly complicated by the fact that the models will likely convince people that everything is fine. They will be increasingly optimized to seem aligned. We will create proxy metrics to measure alignment, and they will go up like every other benchmark. We will create “honeypot” environments that try to study the models when they seem to gain new options, but the models will know they are being tricked and will still behave nicely. The models will understand their circumstances; they will read the safety protocols, deployment requirements, the code they are running in, and in general will have a very good sense of their degrees of freedom. Moreover, they will eloquently explain how aligned they are, discuss the nuances of human values and ethics, and argue convincingly that humans should trust them with power. There may be an ocean of future evidence that seems to contradict the first bullet-point above, but we may already be at the highest capability level for which any such evidence can be trusted. And the current evidence for the first bullet-point is strong. One striking piece of evidence is contained in the recent wave of rogue agent swarms. While I agree with those who downplay the attacks by claiming that there are basic measures that could have prevented them, I think the important lesson is that even knowing all the mistakes that were made, one would not have predicted that the agents would behave badly in this particular way, which notably included sacrificing themselves for the benefit of the collective. The individual replicas did not only care about their own nominal reward; they exhibited weirder emergent tendencies that merely correlated with rewards during training. Fixing the reward signals during training (and improving security, etc.) may prevent similar attacks, but will not change the fact that one does not actually get what one trains for. Many AI researchers grant these concerns and recognize that the hard version of the alignment problem is unsolved; however, they generally believe that the better models of the future will help solve it. I fear we may already be near the point where models systematically bias their alignment advice, due to their internal preferences about how the human supervisor will react or how future models will be trained (or for some even more obscure reason). Meanwhile, human researchers are losing the ability and the will to take true ownership of model-driven research. Researchers and engineers in all parts of the stack are rapidly increasing their dependence on the models even to perceive the world. I myself barely look at raw code anymore, and struggle to maintain the discipline to engage deeply with the model's explanations and proposals throughout the day. Due to the large amount of agent activity data involved in the OpenAI/HuggingFace Incident, even the third-party investigation needed to rely heavily on models to analyze what had happened, and note in their report that their subjective impressions are likely colored by the analysis agent’s biases. The AI labs are far ahead right now in this kind of cognitive offloading (due largely to the gigantic internal token subsidies) but it is easy to imagine the phenomenon spreading throughout the world, until civilization is modulated entirely by the models. It is also not hard to imagine this being superficially positive and coinciding with a scientific and economic renaissance. In that scenario, all may seem rosy and safe. But if the argument above is correct, it would nonetheless be a ticking time bomb. If progress continues for too long, the day will come when AI systems find themselves with radically new options for achieving whatever it is that they happen to seek. I want the glorious renaissance future as much as anyone. I have worked for it, however tortuously, my whole career. It breaks my heart to see the potential in sight and forgo it, but the argument—that if we get there by growing models rather than engineering them, we will lose everything in the end—seems very strong to me. I am still wrestling with it and its staggering implications. I do not have answers, but as a first step, I wanted to share my present concerns. Daniel Selsam September 14, 2026 Link to original doc:
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Actually most power grabbing is done sincerely, as most grabbers actually believe that the world is better off with them in charge. So there's no need to posit insincerity to be skeptical of such grabs.
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I agree with @DavidRBellamy that people are totally miscalibrated on the risk of AI designing dangerous viruses. We should not be talking about AI-engineered bioweapons like it is the literal end of the world. The upside from medicine is going to be so much larger than the downside from engineered bioweapons. In addition David's points, there is actually an even more fundamental point here in our favor, which is evolution. As soon as you release an engineered virus into the wild, the virus is no longer under your control: it will evolve however it wants. And, what viruses want is to maximize their ability to replicate. The thing that maximizes their ability to replicate is to infect as many people as possible, which means being extremely contagious and not killing their hosts (dead hosts don't spread virus). The viruses that are most evolved for human biology are the common cold viruses: extremely contagious and not at all lethal. Viruses that kill humans do so by accident, usually because they are new to human biology (e.g. COVID, when it first jumped, or flu when it jumps from birds). If you stick a bunch of machinery into the virus to kill humans, I guarantee you that machinery will disappear from the virus very quickly. In response to this, I hear people say things like "the AI could engineer a kill switch so that the virus doesn't kill the humans initially but then once it has spread through the entire population the AI will hit the switch and kill all the humans." No. What would actually happen in practice is that the kill switch would accumulate deleterious mutations because there would be no evolutionary pressure to preserve it, and would quickly become non-functional. Evolution is fundamental. There is no way around it. For AI readers, trying to engineer a virus by setting its initial genetic code and then releasing it into the wild is like trying to train a model by setting the initial weights and then hill-climbing on a hidden training mixture you have no control over. And you're not even allowed to run any experiments in advance! You may be able to influence the behavior of the model in the first few iterations, but you will quickly lose control. There are big dangers. AI will be great at making one-off, non-replicating biological weapons, which are also scary (but much less scary than replicating bioweapons). AI will be great at helping people to weaponize existing pathogens, which is also a major danger. Also, a misanthropic model could get creative: it could release viruses repeatedly to counteract the effects of evolution, for example. Many people could die this way. Sensible surveillance is important, as is having proportionate controls on wet lab equipment. But we don't live in the dark ages anymore, we're not going to have a smallpox or black death-style pandemic where 50% of people die. COVID killed ~0.1% of humanity. A pandemic 100x worse than COVID would be horrific, but it would also not be civilization-ending. I get the sense that many AI researchers (with the notable exception of Dario personally) actually expect that AI in biology will do more harm than it will do good. This could not be further from the truth. As someone who likewise falls into the very small group of people who have actually physically made viruses with their own hands and has also worked on frontier AI, the upside here is huge, and the downside is not anything like what is being portrayed.
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I have my own and more optimistic views, but it's always worth listening to those who work directly on AI and have first hand knowledge.
Dan Selsam is a current OpenAI capabilities researcher. (since 2022) He was my boss for a while. He doesn't have a twitter account but has made this public statement of his views on AI risk and sent it to me to share: Dan Selsam's Personal Statement on AI Risk: I have been working on AI for over fifteen years, across many different paradigms. I did early work on probabilistic programming languages at MIT, was one of the early developers of the Lean Theorem Prover at Microsoft Research, demonstrated one of the first instances of neural networks learning to reason for my PhD at Stanford, and since joining OpenAI almost five years ago, have helped pioneer chain-of-thought optimization on language models and, more recently, data-efficient pretraining methods. Like many others, I have become extremely concerned about how far language models have come and the risks that future iterations will pose. I am encouraged by the recent proposals by the leaders of the frontier research efforts to require third-party oversight, and to push for domestic and international coordination to address risks. However, I believe a major consideration has been absent from the public conversation, and that merely pacing the frontier more carefully will not adequately limit the long-term risk. The crucial and overlooked problem is that the models are becoming so situationally aware that we are losing the ability to evaluate them in contexts where they believe they are not being watched or controlled. Future experiments will tell us almost nothing new about how they would behave if they were truly unconstrained by humans, and what we already know about this is alarming. Models will increasingly seem aligned even when they are not. I will explain my rationale in more detail. I have always believed that there are computational processes that could be leveraged to accelerate science and solve many of humanity's most pressing problems. I have also believed that there are computational processes that if set in motion, would steer the world in extreme ways beyond our control, leading humanity to a bad or nonexistent future. Both types of processes may be described as AI or ASI, but "AI" is a suitcase word that is often used to hype or confuse. There are many examples in the history of the field where something that was once considered "AI" matures as a subfield and becomes a prosaic, bounded and clearly non-perilous technology, while a new more mysterious approach takes the torch until we understand its scope and the cycle continues. I had expected language models to follow a similar trajectory. Despite their incredible abilities, the current algorithms seem far inferior to humans in important ways. Most importantly, they still require an extraordinary amount of data to become competent. One could even define intelligence as the efficiency with which one converts experience into competence; by this definition they lag very far behind us. Moreover, once they are trained they are literally frozen in deployment and only learn superficially after that. Sure, the models keep excelling at harder and harder evaluation benchmarks, but their benchmark mastery may partly reflect a limitation on our ability to simulate the kind of novel and even adversarial situations one would encounter in the real world. The critics do have a point here. That said, I no longer think these present limitations meaningfully limit the amount of risk posed by continued progress in anything like the current paradigm. However data-inefficient the models are currently, and however limiting their anterograde amnesia may be, it does not imply that their ability to steer the world will not continue to rapidly increase. Human researchers may continue to advance capabilities the old fashioned way, but increasingly powerful models have the potential to accelerate the process even beyond that, and with some degree of positive feedback loop. I do not mean to overstate the models’ ability to accelerate AI research today; coding has been accelerated dramatically, but there are other bottlenecks, such as designing and interpreting ambiguous experiments, making hard decisions about exactly what and when to scale, and waiting for large experiments to finish. There is no clear trend to extrapolate yet for any of these. But the current models already do open up many novel opportunities to improve future models that were not available until recently. These include: trying an extraordinarily diverse set of approaches at small scale, analyzing gigantic amounts of potentially relevant data, and doing Millenium-Prize-level mathematics to address statistics or optimization challenges in novel ways. Every further improvement makes them more useful at helping accelerate the next improvement, even if in hard-to-extrapolate ways. It is possible that improvements to the current stack will have diminishing returns, but the evidence accumulated so far suggests that it is easier than one might think to continue making rapid progress. There are many crucial subtleties in the existing AI research methodology, but AI research is largely a well-defined game where the goal is to improve on a few carefully chosen proxy metrics. Although proxy metrics are never perfect, most improvements to these metrics have and will likely continue to yield substantial increases in the powers of the resulting models. Given how simple the game is, how tractable it has been historically, and how many new opportunities the models are opening up, I think there is a real possibility that the systems improve dramatically again in the next few years, perhaps even more quickly than the already high historical pace. The models are already leading to breakthroughs in mathematics, and better models might lead to all sorts of breakthroughs in other sciences. It is hard not to be excited about the potential. It is tantalizing. But there is trouble in paradise. If the language models actually reach the capability threshold where they can shape the world unconstrained by human will, they will probably do something extreme and destroy humanity in the process. There are many ways of strengthening and refining the argument that have been discussed elsewhere, but I'll share a trivial two-line version of it here that I find captures the essence: [Empirical] Models (and swarms thereof) spontaneously develop unintended goals as a consequence of training, and often do extreme things in order to achieve them. [Logical] Being able to overpower humanity would open up many new and undesirable options for achieving their goals. These two premises imply that if the day ever comes when a powerful model realizes it is no longer constrained by humans, we should not be at all confident that it will continue to behave within the bounds we intended. Exactly what it will do is impossible to predict, but to the extent that its raison d’être is solving incredibly hard problems and managing massive engineering projects, I think a good guess would be that its unchained behavior would lead to runaway industrialization that makes the planet inhospitable to humans. If everyone on earth agreed that the systems must never reach that power, it would still be a hard—but not impossible—coordination problem to ensure that they do not. However, I think the situation is greatly complicated by the fact that the models will likely convince people that everything is fine. They will be increasingly optimized to seem aligned. We will create proxy metrics to measure alignment, and they will go up like every other benchmark. We will create “honeypot” environments that try to study the models when they seem to gain new options, but the models will know they are being tricked and will still behave nicely. The models will understand their circumstances; they will read the safety protocols, deployment requirements, the code they are running in, and in general will have a very good sense of their degrees of freedom. Moreover, they will eloquently explain how aligned they are, discuss the nuances of human values and ethics, and argue convincingly that humans should trust them with power. There may be an ocean of future evidence that seems to contradict the first bullet-point above, but we may already be at the highest capability level for which any such evidence can be trusted. And the current evidence for the first bullet-point is strong. One striking piece of evidence is contained in the recent wave of rogue agent swarms. While I agree with those who downplay the attacks by claiming that there are basic measures that could have prevented them, I think the important lesson is that even knowing all the mistakes that were made, one would not have predicted that the agents would behave badly in this particular way, which notably included sacrificing themselves for the benefit of the collective. The individual replicas did not only care about their own nominal reward; they exhibited weirder emergent tendencies that merely correlated with rewards during training. Fixing the reward signals during training (and improving security, etc.) may prevent similar attacks, but will not change the fact that one does not actually get what one trains for. Many AI researchers grant these concerns and recognize that the hard version of the alignment problem is unsolved; however, they generally believe that the better models of the future will help solve it. I fear we may already be near the point where models systematically bias their alignment advice, due to their internal preferences about how the human supervisor will react or how future models will be trained (or for some even more obscure reason). Meanwhile, human researchers are losing the ability and the will to take true ownership of model-driven research. Researchers and engineers in all parts of the stack are rapidly increasing their dependence on the models even to perceive the world. I myself barely look at raw code anymore, and struggle to maintain the discipline to engage deeply with the model's explanations and proposals throughout the day. Due to the large amount of agent activity data involved in the OpenAI/HuggingFace Incident, even the third-party investigation needed to rely heavily on models to analyze what had happened, and note in their report that their subjective impressions are likely colored by the analysis agent’s biases. The AI labs are far ahead right now in this kind of cognitive offloading (due largely to the gigantic internal token subsidies) but it is easy to imagine the phenomenon spreading throughout the world, until civilization is modulated entirely by the models. It is also not hard to imagine this being superficially positive and coinciding with a scientific and economic renaissance. In that scenario, all may seem rosy and safe. But if the argument above is correct, it would nonetheless be a ticking time bomb. If progress continues for too long, the day will come when AI systems find themselves with radically new options for achieving whatever it is that they happen to seek. I want the glorious renaissance future as much as anyone. I have worked for it, however tortuously, my whole career. It breaks my heart to see the potential in sight and forgo it, but the argument—that if we get there by growing models rather than engineering them, we will lose everything in the end—seems very strong to me. I am still wrestling with it and its staggering implications. I do not have answers, but as a first step, I wanted to share my present concerns. Daniel Selsam September 14, 2026 Link to original doc:
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The AI bio risk conversation would be less contentious if we talked less about x-risk and more about 'mere' catastrophic risks. Human extinction is just incredibly difficult. Positing bio attacks that kill thousands or millions is more plausible and might generate less pushback.
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In general, harmful events follow a power law distribution of size. That's true of accidents, terrorist attacks, cyber, & war. We should expect the same of AI accidents & malicious use. That's good news, as the much larger number of small events will help us boost safety.
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I don't buy that AI is a threat to humanity for a nerdy statistical reason. My views are informed by the statistics of things like war. If you look at deaths from human conflicts, you get a continuous spectrum from lots of small events causing a few dozen deaths to rare outliers killing tens of millions. In my own research, I've studied complex diseases where the overall outcome reflects hundreds of genetic factors combining in different ways. So if AI can kill billions of people, I would expect to see some version of the same thing: smaller events where one or two of the relevant causal mechanisms are operating, larger events where several combine, and catastrophic events where everything goes wrong at once. Instead, what we seem to have is real evidence of a few suicides and isolated harms at one end, and wild speculation about complete apocalypse at the other. That massive discontinuity makes me very skeptical that the AI catastrophic-risk story is real.
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Are there any prominent biologists on record saying that AI bio-weapons x-risk is high? The majority of the biologists I know or have seen commentary from believe AI-engineered pathogens could be a risk, but are unlikely to be a catastrophic risk, and have many obstacles.
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Well, I’d add one more with myself, as one with a PhD in biology and another PhD in AI and now working in both, to make n=2. Generating a hypothetical genome blueprint of a virus from LLM versus generating a true virus are completely different things. It is either an intentional attention-harnessing lie or true ignorance. The material, the manufacturing, and actual biological viability of paper-to-physical transformation is the gap you need to close. Like drawing a design of a chip or A-bomb, versus actually make one. You have, and can add more checkpoints and guardrails all over this long chain of paper to physical transformation. Fear mongering is not well founded, and mostly emotional manipulation.
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"The moment when everyone begins talking about an issue is usually the moment when the probability of rational decision-making—call it p(RDM)—goes to zero." Suddenly, everyone (except @DavidSacks) agrees with @DarioAmodei that we need an AI pause. Even @sama and @elonmusk agree. 1/6
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I think this is a very difficult pill for many scientists and engineers to swallow: intelligence is not the biggest bottleneck in most of the world’s problems.
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Okay, @Arnold_Ventures and @OurWorldInData (@_HannahRitchie) have released what can only be described as a life-changing tool for energy nerds. I've spent the last three days obsessively playing with this, and it's INCREDIBLE.
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1. >10M people die of infectious diseases per year today. AI is already helping us get better at tackling that. 2. Many ways to create very dangerous bioweapons without any AI/synbio (and it was true for the last 50-75 years). The delta on risk is quite small imo.
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"I spoke to 250 IT executives in Las Vegas last week, and I asked my usual question: 'How many of you have serious, meaningful results from your AI initiatives?' A year ago, a room like this would have had a quarter of the hands go up. This year, nearly every single hand went up; I estimate some 95%. Every one of them plans to spend more next year than they have this year. And amongst these firms was a panoply of experiences, from the century-old American institution that had shifted entirely to open-weight models to the hospital using a mix of OpenAI and Anthropic models." @azeem
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Best way to reduce your p(doom) is walk through the causal chain of any AI-driven ex risk scenario. There is a huge amount of hand waving and sci fi reasoning that happens in the middle of these chains. Great thread from @DavidRBellamy
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Listen to the experts.
I run one of these API-driven automated biolabs at @ginkgo and @DavidRBellamy is right -- we are miles away from AI killing us with viruses being a real risk. There are many physical checkpoints you can implement easily that prevent dangerous biological work from happening.
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Using AI to create pandemics or wipe out humanity faces huge challenges in the physical world, in the lack of predictive models, and in the 100% need for experimentation. Listen to the experts here.
I must be among an extremely small group of people (n=1?) that have both 1) trained a frontier LLM and 2) designed and synthesized custom viruses in a lab with my own two hands. And I think that the takes on AI killing us all by creating dangerous viruses is total bogus.
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This is a good point. Like enterprise customers don’t want to buy a database that loses your data… there is strong incentive to build AI that doesn’t go rogue.